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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nlrp3
Name: NLR family, pyrin domain containing 3
Acc ID: CHEBI:17754
Term: glycerol
Definition: A triol with a structure of propane substituted at positions 1, 2 and 3 by hydroxy groups.
Chemical ID: MESH:D005990
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nlrp3increases expressionEXP 6480464CTDGlycerol results in increased expression of NLRP3 proteinPMID:36690085
Nlrp3multiple interactionsEXP 6480464CTDPentoxifylline inhibits the reaction [Glycerol results in increased expression of NLRP3 protein]; Thiamine inhibits the reaction [Glycerol results in increased expression of NLRP3 protein]PMID:36690085
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