GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Nlrp3 | decreases expression | ISO | Nlrp3 (Mus musculus) | 6480464 | CTD | Melatonin results in decreased expression of NLRP3 mRNA | PMID:36504304 | Nlrp3 | multiple interactions | ISO | NLRP3 (Homo sapiens) | 6480464 | CTD | Melatonin inhibits the reaction [arsenite results in increased expression of NLRP3 protein] | PMID:36343453 | Nlrp3 | multiple interactions | ISO | Nlrp3 (Mus musculus) | 6480464 | CTD | [Nickel co-treated with Melatonin] results in decreased expression of NLRP3 protein; [SELENOM protein affects the susceptibility to Melatonin] which affects the expression of NLRP3 protein; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 mRNA]; Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of NLRP3 protein]; Nickel inhibits the reaction [Melatonin results in decreased expression of NLRP3 mRNA] | PMID:36504304 | |
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