Liposaccharide natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria).
Chemical ID:
MESH:D008070
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; [sodium arsenite co-treated with Lipopolysaccharides] promotes the reaction [SERPINH1 protein binds to NLRP3 protein]; [sodium arsenite co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; FBXO3 protein inhibits the reaction [MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]]; FBXO3 protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Lipopolysaccharides inhibits the reaction [Omeprazole inhibits the reaction [Cisplatin results in increased expression of NLRP3 protein]]; MIR219A1 mRNA inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; N-(1,2,3,5,6,7-hexahydro-S-indacen-4-ylcarbamoyl)-4-(2-hydroxy-2-propanyl)-2-furansulfonamide inhibits the reaction [[sodium arsenite co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of IL1B protein modified form]; NLRP3 protein promotes the reaction [[Zearalenone co-treated with Lipopolysaccharides] results in increased expression of TNF protein]; Taurine inhibits the reaction [[Arsenic Trioxide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]
2-chloro-5-nitrobenzanilide inhibits the reaction [Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]]; 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; [Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Adenosine Triphosphate co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; [Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate co-treated with Resveratrol] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 mRNA; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; [Silicon Dioxide co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; [Uric Acid co-treated with Lipopolysaccharides] results in increased activity of NLRP3 protein; acanthoic acid inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Apigenin analog inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]]; Apigenin analog inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]]; Apigenin inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]]; Apigenin inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]]; apigenin-6,8-di-C-glycopyranoside inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Cannabidiol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Coal Tar promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; cordycepin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; CRT 0066101 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NLRP3 protein]; KN 62 inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Lipopolysaccharides inhibits the reaction [swietenine inhibits the reaction [Glucose results in increased expression of NLRP3 protein]]; Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]; Lipopolysaccharides promotes the reaction [Coal Tar results in increased expression of NLRP3 mRNA]; Lipopolysaccharides promotes the reaction [Coal Tar results in increased expression of NLRP3 protein]; Lipopolysaccharides promotes the reaction [Glucose results in increased expression of NLRP3 protein]; Luteolin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; NLRP3 protein affects the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; NLRP3 protein affects the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; NLRP3 protein inhibits the reaction [PRKAA1 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]]; NLRP3 protein inhibits the reaction [PRKAA1 protein inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; NLRP3 protein promotes the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; NLRP3 protein promotes the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of IL1B protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; puerarin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Quercetin inhibits the reaction [NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]]; Quercetin inhibits the reaction [NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]]; Quercetin inhibits the reaction [NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]]; Quercetin inhibits the reaction [NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]]; Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]
1-dodecylsulfonyl-5N,6O-oxomethylidenenojirimycin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; [Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]; [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NLRP3 protein; [Lipopolysaccharides co-treated with Uric Acid] affects the localization of NLRP3 protein; [Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]; [triptolide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 mRNA; [triptolide co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Carticaine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; CNR2 protein affects the reaction [[Dextran Sulfate co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; cordycepin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; CRT 0066101 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NLRP3 protein]; Dexamethasone inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Dexmedetomidine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] affects the localization of NLRP3 protein]; diallyl trisulfide inhibits the reaction [[Lipopolysaccharides co-treated with Uric Acid] promotes the reaction [PYCARD protein binds to CASP1 protein binds to IL1B protein binds to NLRP3 protein]]; epigallocatechin gallate inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; epigallocatechin gallate inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; eriodictyol inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; formononetin inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 mRNA]; KCNJ10 protein promotes the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; lycium barbarum polysaccharide inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Memantine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with [Aluminum Hydroxide co-treated with Magnesium Hydroxide]] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of and results in increased cleavage of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Alum Compounds] results in increased cleavage of and results in increased secretion of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of IL6 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PYCARD protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of TNF protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Silicon Dioxide] results in increased secretion of and results in increased cleavage of IL1B protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased cleavage of CASP1 protein]; NLRP3 protein affects the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased secretion of and results in increased cleavage of IL1B protein]; NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with aluminum sulfate] results in increased secretion of IL1B protein]; NLRP3 protein promotes the reaction [[Lipopolysaccharides co-treated with nickel chloride] results in increased secretion of IL1B protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in decreased expression of BECN1 mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in decreased expression of BECN1 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in decreased expression of MAP1LC3B mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of SQSTM1 mRNA]; NLRP3 protein promotes the reaction [Lipopolysaccharides results in increased expression of SQSTM1 protein]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to CASP1 protein]]; PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PYCARD protein]]; prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; S-allylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Galactosamine] results in increased expression of NLRP3 protein]; sulforaphane inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NLRP3 protein]
