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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308205
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Pard6b
Name: par-6 family cell polarity regulator beta
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Pard6bincreases expressionEXP 6480464CTDbisphenol A results in increased expression of PARD6B mRNAPMID:25181051
Pard6bincreases methylationEXP 6480464CTDbisphenol A results in increased methylation of PARD6B genePMID:28505145
Pard6bdecreases expressionISOPard6b (Mus musculus)6480464CTDbisphenol A results in decreased expression of PARD6B mRNAPMID:26063408
Pard6bdecreases methylationISOPard6b (Mus musculus)6480464CTDbisphenol A results in decreased methylation of PARD6B promoterPMID:27312807
Pard6bincreases expressionISOPARD6B (Homo sapiens)6480464CTDbisphenol A results in increased expression of PARD6B mRNAPMID:36232920
Pard6bincreases expressionISOPard6b (Mus musculus)6480464CTDbisphenol A results in increased expression of PARD6B mRNAPMID:32156529 PMID:33221593
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