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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307303
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ndrg1
Name: N-myc downstream regulated 1
Acc ID: CHEBI:53001
Term: nickel sulfate
Definition: A metal sulfate having nickel(2+) as the metal ion.
Chemical ID: MESH:C029938
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ndrg1affects expressionISONdrg1 (Mus musculus)6480464CTDnickel sulfate affects the expression of NDRG1 mRNAPMID:12718980
Ndrg1increases expressionISONDRG1 (Homo sapiens)6480464CTDnickel sulfate results in increased expression of NDRG1 mRNA; nickel sulfate results in increased expression of NDRG1 proteinPMID:16288478 PMID:17382205
Ndrg1multiple interactionsISONDRG1 (Homo sapiens)6480464CTDAscorbic Acid inhibits the reaction [nickel sulfate results in increased expression of NDRG1 protein]PMID:16288478
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