Gene Term Annotation Report - Rat Genome Database

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GENE - TERM ANNOTATION REPORT

RGD ID:	1307174
Species:	Rattus norvegicus
RGD Object:	Gene
Symbol:	Abca3
Name:	ATP binding cassette subfamily A member 3

Acc ID:	GO:0030324
Term:	lung development
Definition:	The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
Definition Source(s):	GOC:jid, UBERON:0002048

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
Abca3	involved_in	ISO	Abca3 (Mus musculus)	1624291	RGD	MGI:3722561 PMID:17540762 MGI:6356490 PMID:20190032	MGI:3722561 MGI:6356490 PMID:17540762 PMID:20190032
Abca3	involved_in	ISS	UniProtKB:Q8R420	1600115	UniProt	GO_REF:0000024	GO_REF:0000024

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