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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307012
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Papss2
Name: 3'-phosphoadenosine 5'-phosphosulfate synthase 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Papss2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of PAPSS2 mRNAPMID:25181051
Papss2increases expressionEXP 6480464CTDbisphenol A results in increased expression of PAPSS2 mRNAPMID:30816183 PMID:32528016
Papss2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of PAPSS2 genePMID:28505145
Papss2multiple interactionsEXP 6480464CTD[bisphenol A co-treated with Estradiol] results in decreased expression of PAPSS2 mRNAPMID:26496021
Papss2decreases expressionISOPapss2 (Mus musculus)6480464CTDbisphenol A results in decreased expression of PAPSS2 mRNAPMID:32156529
Papss2increases expressionISOPAPSS2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of PAPSS2 mRNAPMID:31715268
Papss2increases expressionISOPapss2 (Mus musculus)6480464CTDbisphenol A results in increased expression of PAPSS2 mRNAPMID:30951980
Papss2multiple interactionsISOPAPSS2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of PAPSS2 genePMID:31601247
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