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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1306078
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2s1
Name: cytochrome P450, family 2, subfamily s, polypeptide 1
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2s1decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of CYP2S1 mRNAPMID:25181051
Cyp2s1increases expressionEXP 6480464CTDbisphenol A results in increased expression of CYP2S1 mRNAPMID:34947998
Cyp2s1affects expressionISOCYP2S1 (Homo sapiens)6480464CTDbisphenol A affects the expression of CYP2S1 mRNAPMID:36466761
Cyp2s1decreases expressionISOCYP2S1 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of CYP2S1 mRNA; bisphenol A results in decreased expression of CYP2S1 proteinPMID:31715268 PMID:37567409
Cyp2s1increases expressionISOCyp2s1 (Mus musculus)6480464CTDbisphenol A results in increased expression of CYP2S1 mRNAPMID:32156529 PMID:34585602
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