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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1305577
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Mcm2
Name: minichromosome maintenance complex component 2
Acc ID: CHEBI:33216
Term: bisphenol A
Definition: A bisphenol that is 4,4'-methanediyldiphenol in which the methylene hydrogens are replaced by two methyl groups.
Chemical ID: MESH:C006780
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Mcm2affects expressionEXP 6480464CTDbisphenol A affects the expression of MCM2 mRNAPMID:25181051 PMID:32145629
Mcm2decreases expressionEXP 6480464CTDbisphenol A results in decreased expression of MCM2 mRNAPMID:34947998
Mcm2increases methylationEXP 6480464CTDbisphenol A results in increased methylation of MCM2 genePMID:28505145
Mcm2affects expressionISOMCM2 (Homo sapiens)6480464CTDbisphenol A affects the expression of MCM2 mRNAPMID:30903817
Mcm2affects methylationISOMcm2 (Mus musculus)6480464CTDbisphenol A affects the methylation of MCM2 promoterPMID:27334623
Mcm2decreases expressionISOMCM2 (Homo sapiens)6480464CTDbisphenol A results in decreased expression of MCM2 mRNA; bisphenol A results in decreased expression of MCM2 proteinPMID:29275510 PMID:37567409
Mcm2increases expressionISOMCM2 (Homo sapiens)6480464CTDbisphenol A results in increased expression of MCM2 mRNA; bisphenol A results in increased expression of MCM2 proteinPMID:16474171 PMID:17268063 PMID:33516137
Mcm2multiple interactionsISOMCM2 (Homo sapiens)6480464CTD[bisphenol A co-treated with Fulvestrant] results in increased methylation of MCM2 genePMID:31601247
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