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GENE - TERM ANNOTATION REPORT

RGD ID: 12500291
Species: Ictidomys tridecemlineatus
RGD Object: Gene
Symbol: Ccl22
Name: C-C motif chemokine ligand 22
Acc ID: GO:0008009
Term: chemokine activity
Definition: The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
Definition Source(s): GOC:BHF, GOC:rl, PMID:12183377, Wikipedia:Chemokine
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ccl22enablesIEAInterPro:IPR000827 or InterPro:IPR001811 or InterPro:IPR036048 or InterPro:IPR039809150520179InterPro GO_REF:0000002
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