GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Sod2 | decreases expression | ISO | Sod2 (Rattus norvegicus) | 6480464 | CTD | alpha-Tocopherol results in decreased expression of SOD2 protein | PMID:18942769 | Sod2 | increases expression | ISO | Sod2 (Rattus norvegicus) | 6480464 | CTD | alpha-Tocopherol results in increased expression of SOD2 mRNA; alpha-Tocopherol results in increased expression of SOD2 protein | PMID:22732938 | Sod2 | multiple interactions | ISO | Sod2 (Rattus norvegicus) | 6480464 | CTD | [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; alpha-Tocopherol inhibits the reaction [Malathion results in increased activity of SOD2 protein]; alpha-Tocopherol inhibits the reaction [Triiodothyronine, Reverse results in increased expression of and results in increased activity of SOD2 protein] | PMID:16135673 PMID:20194575 PMID:23859036 | | ||||||||||||||||||||||
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