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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 11217
Species: Mus musculus
RGD Object: Gene
Symbol: Rarb
Name: retinoic acid receptor, beta
Acc ID: CHEBI:17336
Term: all-trans-retinol
Definition: A retinol in which all four exocyclic double bonds have E- (trans-) geometry.
Chemical ID: MESH:D014801
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Rarbdecreases expressionEXP 6480464CTDVitamin A results in decreased expression of RARB mRNAPMID:30944279
Rarbaffects expressionISORarb (Rattus norvegicus)6480464CTDVitamin A affects the expression of RARB mRNAPMID:14529804 PMID:16530976
Rarbdecreases expressionISORarb (Rattus norvegicus)6480464CTDVitamin A deficiency results in decreased expression of RARB mRNAPMID:7519440
Rarbdecreases expressionISORARB (Homo sapiens)6480464CTDVitamin A results in decreased expression of RARB mRNAPMID:17034753
Rarbincreases expressionISORARB (Homo sapiens)6480464CTDVitamin A results in increased expression of RARB mRNAPMID:15754000
Rarbmultiple interactionsISORarb (Rattus norvegicus)6480464CTD[R 115866 co-treated with Vitamin A] results in increased expression of RARB mRNA; Tretinoin inhibits the reaction [Vitamin A affects the expression of RARB mRNA]; Vitamin A inhibits the reaction [Safflower Oil results in decreased expression of RARB mRNA]PMID:15203375 PMID:16530976 PMID:17510468
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