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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:8207
Term: (+)-pilocarpine
Definition: The (+)-enantiomer of pilocarpine.
Chemical ID: MESH:D010862
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiaincreases expressionEXP 6480464CTDPilocarpine results in increased expression of NFKBIA mRNAPMID:15193289
Nfkbiaincreases phosphorylationISONfkbia (Rattus norvegicus)6480464CTDPilocarpine results in increased phosphorylation of NFKBIA proteinPMID:23211629
Nfkbiamultiple interactionsISONfkbia (Rattus norvegicus)6480464CTDresveratrol inhibits the reaction [Pilocarpine results in increased phosphorylation of NFKBIA protein]; Sirolimus inhibits the reaction [Pilocarpine results in increased phosphorylation of NFKBIA protein]PMID:23211629
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