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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10975
Species: Mus musculus
RGD Object: Gene
Symbol: Nfkbia
Name: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
Acc ID: CHEBI:27958
Term: cocaine
Definition: A tropane alkaloid obtained from leaves of the South American shrub Erythroxylon coca.
Chemical ID: MESH:D003042
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfkbiaaffects expressionEXP 6480464CTDCocaine affects the expression of NFKBIA mRNAPMID:15681117
Nfkbiaincreases phosphorylationEXP 6480464CTDCocaine results in increased phosphorylation of NFKBIA proteinPMID:20354174
Nfkbiaaffects expressionISONfkbia (Rattus norvegicus)6480464CTDCocaine affects the expression of NFKBIA mRNAPMID:20187946
Nfkbiaincreases activityISONfkbia (Rattus norvegicus)6480464CTDCocaine results in increased activity of NFKBIA proteinPMID:19183502
Nfkbiamultiple interactionsISONfkbia (Rattus norvegicus)6480464CTDSCH 23390 inhibits the reaction [Cocaine results in increased activity of NFKBIA protein]PMID:19183502
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