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Ontology Browser
Term:
Parent Terms Term With Siblings Child Terms
altered glycosaminoglycan pathway +  
chondroitin sulfate biosynthetic pathway  
dermatan sulfate biosynthetic pathway 
glycosaminoglycan degradation pathway  
heparan sulfate biosynthetic pathway +   
hyaluronan metabolic pathway 
keratan sulfate biosynthetic pathway  
Those metabolic reactions involved in the biosynthesis of keratan sulfate - a glycosaminoglycan found in the cornea, in cartilage, and in the nucleus pulposus and also as the accumulation product in Morquio's syndrome. It consists of repeating disaccharide units in specific linkage, each composed of a sulfated N-acetylglucosamine residue linked to one of galactose, which is usually sulfated. There are two forms, keratan sulfate I and keratan sulfate II, which differ in carbohydrate content and localization; the former occurs in the cornea and the latter in skeletal tissues.

Synonyms
Related Synonyms: Keratan sulfate biosynthesis ;   keratan sulfate biosynthetic process
Definition Sources: GO:0018146, KEGG:map00533, OneLook:www.onelook.com, Reactome:R-HSA-2022854

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