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Ontology Browser
Term:
mechanosensitive voltage-gated sodium channel activity (GO:0101013)
Annotations: Rat: (0) Mouse: (0) Human: (0) Chinchilla: (0) Bonobo: (0) Dog: (0) Squirrel: (0) Pig: (0) Naked Mole-rat: (0) Green Monkey: (0)
Parent Terms Term With Siblings Child Terms
mechanosensitive potassium channel activity  
mechanosensitive voltage-gated sodium channel activity 
Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
stretch-activated, monoatomic cation-selective, calcium channel activity +   
voltage-gated sodium channel activity involved in cardiac muscle cell action potential +   

Synonyms
Exact Synonyms: mechanically-modulated voltage-gated sodium channel activity
Definition Sources: PMID:21041530, PMID:26838316

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