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Ontology Browser
Term:
serotonin-activated cation-selective channel complex (GO:1904602)
Annotations: Rat: (2) Mouse: (2) Human: (5) Chinchilla: (2) Bonobo: (5) Dog: (5) Squirrel: (1) Pig: (4) Naked Mole-rat: (2) Green Monkey: (6)
Parent Terms Term With Siblings Child Terms
calcium channel complex +   
intracellular cyclic nucleotide activated cation channel complex  
ionotropic glutamate receptor complex +   
potassium channel complex +   
serotonin-activated cation-selective channel complex  
A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.
sodium channel complex +   

Synonyms
Exact Synonyms: 5-HT-3 receptor complex ;   5-HT3 receptor complex ;   5-hydroxytryptamine receptor 3 complex ;   5HT3 receptor complex
Broad Synonyms: serotonin receptor complex
Definition Sources: GO_REF:0000088, GOC:bhm, GOC:TermGenie, PMID:16116092

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