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Ontology Browser

Term:
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (GO:0002485)
Annotations: Rat: (2) Mouse: (4) Human: (2) Chinchilla: (1) Bonobo: (1) Dog: (1) Squirrel: (1) Pig: (1) Naked Mole-rat: (1) Green Monkey: (1)
Parent Terms Term With Siblings Child Terms
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent  
The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent  

Synonyms
Exact Synonyms: TAP-dependent endogenous peptide antigen processing and presentation via MHC class I via ER pathway
Definition Sources: GOC:add, ISBN:0781735149, PMID:14647477, PMID:15771591

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