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Ontology Browser
Term:
double-strand break repair via homologous recombination (GO:0000724)
Annotations: Rat: (179) Mouse: (178) Human: (190) Chinchilla: (146) Bonobo: (183) Dog: (183) Squirrel: (172) Pig: (180) Naked Mole-rat: (170) Green Monkey: (188)
Parent Terms Term With Siblings Child Terms
DNA double-strand break processing +   
double-strand break repair involved in meiotic recombination  
double-strand break repair via homologous recombination +   
The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
double-strand break repair via nonhomologous end joining +   
double-strand break repair via single-strand annealing +   
mitochondrial double-strand break repair +   
mitochondrial double-strand break repair via homologous recombination  
negative regulation of double-strand break repair +   
positive regulation of double-strand break repair +   
recombinational interstrand cross-link repair  
regulation of double-strand break repair +   
single-strand break repair via homologous recombination +  

Synonyms
Exact Synonyms: HDR ;   HRR ;   Rad51-dependent recombinational repair ;   Rhp51-dependent recombinational repair ;   homologous recombinational repair ;   homology-directed repair
Alternate IDs: GO:0016924
Definition Sources: GOC:elh, PMID:10357855

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