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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:tirofiban drug pathway
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Accession:PW:0001742 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics pathway of tirofiban, a platelet aggregation inhibitor. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug.


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tirofiban pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Itga2b integrin subunit alpha 2b ISO SMPDB SMP:00267 NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO SMPDB SMP:00267 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 6091
    drug pathway 397
      blood and blood forming organs drug pathway 62
        antithrombotic drug pathway 62
          antiplatelet drug pathway 37
            tirofiban drug pathway 2
              tirofiban pharmacodynamics pathway 2
              tirofiban pharmacokinetics pathway 0
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