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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:analgesic and/or antipyretic drug pathway
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Accession:PW:0001546 term browser browse the term
Definition:The pharmacokinetics and pharmacodynamics of compounds used to alleviate pain and/or reduce fever. Examples include the nonsteroidal anti-inflammatory drugs such as aspirin or ibuprofen and the widely used paracetamol, known as acetaminophen, among others.

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acetylsalicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00083 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00083 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00083 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00083 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00083 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00083 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00083 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00083 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00083 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00083 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00083 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00083 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00083 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00083
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00083 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00083 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00083 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00083 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00083 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00083 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00083 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00083 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00083 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00083 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00083 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00083 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
alfentanil pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00413 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00413 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00413 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00413 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00413 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00413 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00413 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00413 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00413
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00413 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00413 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00413 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00413 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00413 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00413 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00413 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00413 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00413 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00413 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00413 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00413 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00413 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00413 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00413 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00413 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00413 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00413 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00413 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00413 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00413 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
antipyrine drug pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00692 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00692 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00692 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00692 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00692 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00692 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00692 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00692 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00692 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00692 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00692 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00692 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00692 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00692
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00692 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00692 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00692 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00692 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00692 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00692 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00692 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00692 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00692 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00692 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00692 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00692 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
buprenorphine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00684 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00684 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00684 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00684 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00684 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00684 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00684 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00684 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00684
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00684 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00684 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00684 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00684 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00684 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00684 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00684 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00684 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00684 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00684 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00684 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00684 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00684 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00684 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00684 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00684 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00684 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00684 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00684 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00684 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00684 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
codeine and morphine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00405 SMP:00406
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00405 SMP:00406 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00405 SMP:00406 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00405 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00406 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr23:77,587,340...77,591,434 JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00406 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00405 SMP:00406 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00406 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00406 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00405 SMP:00406 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00406 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00405 NCBI chr28:13,297,566...13,330,023 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00406 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00406 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00406 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00405 SMP:00406 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00406 NCBI chr26:19,380,496...19,399,596 JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00405 SMP:00406 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00406 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00405 SMP:00406 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00405 SMP:00406 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
codeine and morphine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00621 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00622 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00622 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00622 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00622 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00622 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00621 NCBI chr28:13,297,566...13,330,023 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00621 SMP:00622 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00622 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00622 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00622 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716 		JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00622 NCBI chr26:19,380,496...19,399,596 JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00622 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761 		JBrowse link
diflunisal pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00289 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00289 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00289 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00289 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00289 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00289 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00289 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00289 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00289 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00289 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00289 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00289 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00289 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00289
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00289 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00289 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00289 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00289 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00289 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00289 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00289 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00289 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00289 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00289 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00289 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00289 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
ethylmorphine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00681 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00681 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00681 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00681 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00681 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00681 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00681 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00681 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00681
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00681 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00681 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00681 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00681 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00681 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00681 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00681 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00681 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00681 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00681 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00681 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00681 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00681 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00681 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00681 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00681 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00681 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00681 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00681 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00681 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00681 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
fentanyl pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00415 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00415 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00415 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00415 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00415 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00415 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00415 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00415 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00415
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00415 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00415 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00415 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00415 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00415 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00415 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00415 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00415 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00415 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00415 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00415 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00415 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00415 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00415 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00415 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00415 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00415 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00415 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00415 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00415 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00415 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
heroin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00407 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00407 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00407 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00407 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00407 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00407 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00407 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00407 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00407
G BCHE butyrylcholinesterase ISO SMPDB SMP:00407 NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00407 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00407 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00407 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00407 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00407 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00407 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00407 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00407 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00407 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00407 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00407 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00407 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00407 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G LOC103233018 liver carboxylesterase 1 ISO SMPDB SMP:00407 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00407 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00407 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00407 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00407 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00407 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00407 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00407 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00407 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
heroin pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCHE butyrylcholinesterase ISO SMPDB SMP:00623 NCBI chr15:23,708,121...23,778,027
Ensembl chr15:23,708,155...23,778,286 		JBrowse link
G LOC103233018 liver carboxylesterase 1 ISO SMPDB SMP:00623 NCBI chr 5:41,710,500...41,745,483 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00623 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
hydrocodone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00411 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00411 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00411 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00411 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00411 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00411 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00411 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00411 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00411
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00411 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00411 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00411 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00411 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00411 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00411 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00411 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00411 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00411 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00411 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00411 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00411 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00411 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00411 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00411 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00411 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00411 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00411 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00411 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00411 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00411 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
hydromorphone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00410 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00410 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00410 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00410 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00410 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00410 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00410 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00410 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00410
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00410 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00410 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00410 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00410 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00410 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00410 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00410 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00410 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00410 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00410 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00410 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00410 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00410 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00410 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00410 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00410 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00410 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00410 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00410 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00410 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00410 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
ibuprofen pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00086 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00086 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00086 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00086 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00086 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00086 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00086 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00086 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00086 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00086 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00086 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00086 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00086 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00086 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00086 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00086 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00086 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00086
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00086 NCBI chr22:10,754,976...10,756,617 JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00086 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00086 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00086 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590 		JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00086 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00086 NCBI chr28:13,297,566...13,330,023 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00086 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00086 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00086 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00086 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00086 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00086 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00086 NCBI chr26:19,380,496...19,399,596 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00086 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00086 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00086 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00086 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00086 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00086 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00086 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO SMPDB SMP:00086 NCBI chr 1:10,918,081...10,926,790
Ensembl chr 1:10,918,770...10,925,983 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 ISO SMPDB SMP:00086 NCBI chr 1:10,885,895...10,909,739
Ensembl chr 1:10,886,690...10,910,546 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00086 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
ibuprofen pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00590 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00590 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 ISO SMPDB SMP:00590 NCBI chr 9:88,082,124...88,125,390 JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00590 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00590 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00590 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00590 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00590 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00590 NCBI chr28:13,297,566...13,330,023 JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00590 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00590 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00590 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716 		JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00590 NCBI chr26:19,380,496...19,399,596 JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00590 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00590 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00590 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO SMPDB SMP:00590 NCBI chr 1:10,918,081...10,926,790
Ensembl chr 1:10,918,770...10,925,983 		JBrowse link
G SLC22A8 solute carrier family 22 member 8 ISO SMPDB SMP:00590 NCBI chr 1:10,885,895...10,909,739
Ensembl chr 1:10,886,690...10,910,546 		JBrowse link
indometacin pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00104 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00104 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00104 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00104 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00104 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00104 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00104 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00104 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00104 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00104 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00104 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00104 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00104 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00104
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00104 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00104 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00104 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00104 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G2A phospholipase A2 group IIA ISO SMPDB SMP:00104 NCBI chr20:112,564,414...112,569,735
Ensembl chr20:112,565,165...112,569,786 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00104 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00104 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00104 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00104 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00104 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00104 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00104 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00104 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
ketoprofen pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00085 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00085 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00085 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00085 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00085 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00085 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00085 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00085 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00085 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00085 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00085 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00085 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00085 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00085
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00085 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00085 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00085 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00085 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00085 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00085 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00085 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00085 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00085 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00085 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00085 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00085 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
levacetylmethadol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00677 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00677 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00677 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00677 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00677 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00677 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00677 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00677 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00677
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00677 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00677 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00677 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00677 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00677 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00677 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00677 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00677 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00677 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00677 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00677 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00677 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00677 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00677 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00677 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00677 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00677 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00677 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00677 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00677 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00677 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
levorphanol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00673 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00673 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00673 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00673 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00673 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00673 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00673 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00673 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00673
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00673 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00673 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00673 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00673 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00673 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00673 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00673 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00673 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00673 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00673 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00673 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00673 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00673 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00673 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00673 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00673 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00673 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00673 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00673 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00673 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00673 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
lornoxicam pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00700 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00700 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00700 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00700 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00700 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00700 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00700 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00700 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00700 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00700 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00700 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00700 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00700 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00700
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00700 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00700 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00700 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00700 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00700 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00700 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00700 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00700 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00700 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00700 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00700 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00700 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
magnesium salicylate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00698 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00698 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00698 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00698 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00698 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00698 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00698 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00698 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00698 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00698 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00698 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00698 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00698 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00698
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00698 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00698 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00698 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00698 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00698 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00698 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00698 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00698 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00698 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00698 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00698 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00698 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
methadone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00408 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00408 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00408 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00408 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00408 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00408 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00408 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00408 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00408
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00408 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00408 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00408 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00408 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00408 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00408 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00408 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00408 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00408 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00408 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00408 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00408 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00408 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00408 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00408 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00408 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00408 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00408 NCBI chr28:13,297,566...13,330,023 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00408 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00408 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00408 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00408 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00408 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00408 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00408 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00408 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
methadone pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00624 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 ISO SMPDB SMP:00624 NCBI chr 9:87,981,300...88,025,007 JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00624 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00624 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00624 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00624 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00624 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00624 NCBI chr28:13,297,566...13,330,023 JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00624 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
nalbuphine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00691 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00691 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00691 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00691 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00691 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00691 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00691 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00691 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00691
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00691 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00691 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00691 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00691 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00691 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00691 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00691 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00691 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00691 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00691 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00691 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00691 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00691 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRK1 opioid receptor kappa 1 ISO SMPDB SMP:00691 NCBI chr 8:49,337,308...49,364,724
Ensembl chr 8:49,341,427...49,362,947 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00691 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00691 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00691 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00691 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00691 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00691 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00691 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00691 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
naltrexone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00687 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00687 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00687 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00687 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00687 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00687 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00687 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00687 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00687
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00687 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00687 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00687 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00687 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00687 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00687 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00687 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00687 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00687 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00687 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00687 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00687 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00687 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00687 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00687 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00687 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00687 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00687 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00687 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00687 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00687 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
naproxen pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00120 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00120 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00120 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00120 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00120 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00120 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00120 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00120 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00120 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00120 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00120 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00120 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00120 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00120
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00120 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00120 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00120 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00120 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00120 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00120 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00120 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00120 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00120 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00120 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00120 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00120 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
oxycodone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00409 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00409 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00409 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00409 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00409 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00409 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00409 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00409 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00409
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00409 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00409 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00409 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00409 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00409 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00409 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00409 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00409 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00409 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00409 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00409 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00409 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00409 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00409 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00409 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00409 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00409 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00409 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00409 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00409 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00409 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
oxymorphone pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00412 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00412 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00412 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00412 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00412 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00412 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00412 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00412 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00412
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00412 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00412 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00412 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00412 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00412 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00412 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00412 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00412 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00412 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00412 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00412 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00412 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00412 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00412 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00412 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00412 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00412 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00412 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00412 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00412 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00412 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
paracetamol drug pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00710 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00710 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00710 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00710 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00710 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00710 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00710 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00710 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00710 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00710 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00710 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00710 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00710 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00710
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00710 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00710 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00710 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00710 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00710 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00710 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00710 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00710 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00710 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD
SMPDB		 PMID:23719833 RGD:8552695 SMP:00710 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO RGD
SMPDB		 PMID:23719833 RGD:8552695 SMP:00710 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00710 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
paracetamol pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 ISO SMPDB SMP:00640 NCBI chr21:61,211,044...61,430,691
Ensembl chr21:61,322,748...61,529,274 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) ISO SMPDB SMP:00640 NCBI chr 5:14,972,589...15,164,594
Ensembl chr 5:14,972,646...15,164,567 		JBrowse link
G ABCC2 ATP binding cassette subfamily C member 2 ISO RGD PMID:23462933 RGD:8552693 NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265 		JBrowse link
G ABCC3 ATP binding cassette subfamily C member 3 ISO RGD PMID:23462933 RGD:8552693 NCBI chr16:42,646,316...42,703,124
Ensembl chr16:42,646,812...42,702,852 		JBrowse link
G ABCC4 ATP binding cassette subfamily C member 4 (PEL blood group) ISO RGD
SMPDB		 PMID:23462933 RGD:8552693 SMP:00640 NCBI chr 3:73,821,887...74,106,617
Ensembl chr 3:73,821,134...74,106,579 		JBrowse link
G ABCC5 ATP binding cassette subfamily C member 5 ISO SMPDB SMP:00640 NCBI chr15:5,409,921...5,505,334
Ensembl chr15:5,409,861...5,505,315 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) ISO SMPDB
RGD		 PMID:23462933 RGD:8552693 SMP:00640 NCBI chr 7:36,458,110...36,599,753 JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 ISO SMPDB SMP:00640 NCBI chr26:8,727,996...8,733,254 JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00640 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB
RGD		 PMID:23462933 RGD:8552693 SMP:00640 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G DNAJB11 DnaJ heat shock protein family (Hsp40) member B11 ISO SMPDB SMP:00640 NCBI chr15:2,841,377...2,858,192
Ensembl chr15:2,841,255...2,858,202 		JBrowse link
G ERP29 endoplasmic reticulum protein 29 ISO SMPDB SMP:00640 NCBI chr11:107,244,359...107,255,293
Ensembl chr11:107,244,335...107,256,499 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 ISO SMPDB SMP:00640 NCBI chr 1:6,676,897...6,679,936 JBrowse link
G HSP90B1 heat shock protein 90 beta family member 1 ISO SMPDB SMP:00640 NCBI chr11:99,119,268...99,139,988
Ensembl chr11:99,119,224...99,139,722 		JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO SMPDB SMP:00640 NCBI chr12:12,920,705...12,925,888
Ensembl chr12:12,920,710...12,927,431 		JBrowse link
G HYOU1 hypoxia up-regulated 1 ISO SMPDB SMP:00640 NCBI chr 1:110,418,497...110,431,636
Ensembl chr 1:110,417,942...110,431,590 		JBrowse link
G LOC103230462 sulfotransferase 1A3 ISO RGD
SMPDB		 PMID:23462933 RGD:8552693 SMP:00640 NCBI chr 5:26,469,450...26,474,416 JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00640 NCBI chr28:13,297,566...13,330,023 JBrowse link
G PDIA2 protein disulfide isomerase family A member 2 ISO SMPDB SMP:00640 NCBI chr 5:229,523...233,298
Ensembl chr 5:229,607...233,200 		JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 ISO SMPDB SMP:00640 NCBI chr21:117,574,932...117,601,896
Ensembl chr21:117,574,427...117,601,960 		JBrowse link
G PDIA6 protein disulfide isomerase family A member 6 ISO SMPDB SMP:00640 NCBI chr14:96,801,327...96,828,325
Ensembl chr14:96,801,349...96,828,716 		JBrowse link
G PPIB peptidylprolyl isomerase B ISO SMPDB SMP:00640 NCBI chr26:19,380,496...19,399,596 JBrowse link
G SDF2L1 stromal cell derived factor 2 like 1 ISO SMPDB SMP:00640 NCBI chr19:4,465,795...4,467,882
Ensembl chr19:4,465,797...4,467,761 		JBrowse link
G SULT1E1 sulfotransferase family 1E member 1 ISO SMPDB
RGD		 PMID:23462933 RGD:8552693 SMP:00640 NCBI chr 7:18,313,510...18,330,768
Ensembl chr 7:18,313,238...18,330,741 		JBrowse link
G SULT2A1 sulfotransferase family 2A member 1 ISO SMPDB SMP:00640 NCBI chr 6:41,160,707...41,175,382
Ensembl chr 6:41,159,978...41,175,300 		JBrowse link
pentazocine pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00686 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00686 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00686 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00686 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00686 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00686 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00686 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00686 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00686
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00686 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00686 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00686 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00686 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00686 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00686 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00686 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00686 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00686 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00686 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00686 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00686 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00686 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00686 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00686 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00686 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00686 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00686 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00686 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00686 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00686 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
remifentanil pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00416 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00416 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00416 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00416 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00416 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00416 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00416 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00416 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00416
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00416 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00416 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00416 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00416 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00416 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00416 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00416 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00416 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00416 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00416 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00416 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00416 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00416 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00416 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00416 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00416 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00416 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00416 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00416 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00416 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00416 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
salicylic acid pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00709 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00709 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00709 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00709 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00709 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00709 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00709 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00709 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00709 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00709 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00709 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00709 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00709 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00709
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00709 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00709 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00709 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00709 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00709 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00709 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00709 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00709 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00709 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00709 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00709 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00709 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
sodium salicylate pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO SMPDB SMP:00708 NCBI chr16:6,355,795...6,370,051
Ensembl chr16:6,356,058...6,369,738 		JBrowse link
G ALOX12B arachidonate 12-lipoxygenase, 12R type ISO SMPDB SMP:00708 NCBI chr16:7,454,950...7,470,949
Ensembl chr16:7,455,044...7,469,934 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase ISO SMPDB SMP:00708 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
G ALOX15B arachidonate 15-lipoxygenase type B ISO SMPDB SMP:00708 NCBI chr16:7,425,533...7,435,896
Ensembl chr16:7,425,990...7,435,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO SMPDB SMP:00708 NCBI chr 9:41,085,257...41,145,760
Ensembl chr 9:41,085,361...41,145,331 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00708 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 ISO SMPDB SMP:00708 NCBI chr 9:88,154,131...88,183,915
Ensembl chr 9:88,154,134...88,183,458 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO SMPDB SMP:00708 NCBI chr26:53,390,054...53,403,309
Ensembl chr26:53,390,089...53,404,211 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO SMPDB SMP:00708 NCBI chr20:73,083,312...73,115,174
Ensembl chr20:73,083,389...73,115,077 		JBrowse link
G CYP2U1 cytochrome P450 family 2 subfamily U member 1 ISO SMPDB SMP:00708 NCBI chr 7:55,859,669...55,880,266
Ensembl chr 7:55,859,849...55,879,280 		JBrowse link
G CYP4F3 cytochrome P450 family 4 subfamily F member 3 ISO SMPDB SMP:00708 NCBI chr 6:14,241,352...14,260,799
Ensembl chr 6:14,241,409...14,263,494 		JBrowse link
G CYP4F8 cytochrome P450 family 4 subfamily F member 8 ISO SMPDB SMP:00708 NCBI chr 6:14,211,899...14,229,793
Ensembl chr 6:14,215,337...14,229,509 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO SMPDB SMP:00708 NCBI chr 8:25,603,668...25,659,232
Ensembl chr 8:25,603,735...25,659,345 		JBrowse link
G GGT1 gamma-glutamyltransferase 1 ISO SMPDB SMP:00708
G GPX1 glutathione peroxidase 1 ISO SMPDB SMP:00708 NCBI chr22:10,754,976...10,756,617 JBrowse link
G LOC103218526 carbonyl reductase [NADPH] 1 ISO SMPDB SMP:00708 NCBI chr 2:80,096,743...80,099,982 JBrowse link
G LTA4H leukotriene A4 hydrolase ISO SMPDB SMP:00708 NCBI chr11:91,371,383...91,413,396
Ensembl chr11:91,371,383...91,406,542 		JBrowse link
G LTC4S leukotriene C4 synthase ISO SMPDB SMP:00708 NCBI chr23:81,523,784...81,526,297
Ensembl chr23:81,523,775...81,526,179 		JBrowse link
G PLA2G4B phospholipase A2 group IVB ISO SMPDB SMP:00708 NCBI chr26:41,137,643...41,147,384 JBrowse link
G PRXL2B peroxiredoxin like 2B ISO SMPDB SMP:00708 NCBI chr20:128,964,750...128,969,469
Ensembl chr20:128,964,987...128,967,620 		JBrowse link
G PTGDS prostaglandin D2 synthase ISO SMPDB SMP:00708 NCBI chr12:1,210,567...1,214,631
Ensembl chr12:1,211,487...1,214,531 		JBrowse link
G PTGES prostaglandin E synthase ISO SMPDB SMP:00708 NCBI chr12:8,393,462...8,408,441
Ensembl chr12:8,393,550...8,408,435 		JBrowse link
G PTGIS prostaglandin I2 synthase ISO SMPDB SMP:00708 NCBI chr 2:14,420,318...14,484,667
Ensembl chr 2:14,441,983...14,488,264 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO SMPDB SMP:00708 NCBI chr12:17,195,403...17,218,450
Ensembl chr12:17,192,628...17,218,315 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO SMPDB SMP:00708 NCBI chr25:42,733,535...42,742,463
Ensembl chr25:42,734,771...42,742,429 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO SMPDB SMP:00708 NCBI chr21:108,584,458...108,779,357
Ensembl chr21:108,628,570...108,779,163 		JBrowse link
tramadol pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA1A adrenoceptor alpha 1A ISO SMPDB SMP:00671 NCBI chr 8:24,884,187...24,985,824
Ensembl chr 8:24,885,741...24,983,125 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00671 NCBI chr20:17,319,440...17,351,054
Ensembl chr20:17,315,117...17,351,054 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 ISO SMPDB SMP:00671 NCBI chr20:3,801,044...3,828,680
Ensembl chr20:3,802,887...3,828,692 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00671 NCBI chr 6:36,166,586...36,195,343
Ensembl chr 6:36,166,262...36,195,363 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00671 NCBI chr20:3,759,509...3,794,106
Ensembl chr20:3,759,597...3,793,980 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00671 NCBI chr25:59,898,745...59,925,166
Ensembl chr25:59,895,341...59,925,522 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00671 NCBI chr16:7,030,016...7,035,620
Ensembl chr16:7,030,055...7,037,754 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00671 NCBI chr15:48,691,224...48,742,336
Ensembl chr15:48,690,667...48,742,385 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00671
G CACNA1A calcium voltage-gated channel subunit alpha1 A ISO SMPDB SMP:00671 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 ISO SMPDB SMP:00671 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 ISO SMPDB SMP:00671 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CHRNA4 cholinergic receptor nicotinic alpha 4 subunit ISO SMPDB SMP:00671 NCBI chr 2:851,790...862,685 JBrowse link
G CHRNB2 cholinergic receptor nicotinic beta 2 subunit ISO SMPDB SMP:00671 NCBI chr20:9,245,803...9,255,430
Ensembl chr20:9,247,231...9,253,795 		JBrowse link
G DRD1 dopamine receptor D1 ISO SMPDB SMP:00671 NCBI chr23:77,587,340...77,591,434 JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00671 NCBI chr 1:109,187,301...109,199,729
Ensembl chr 1:109,186,886...109,198,267 		JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 ISO SMPDB SMP:00671 NCBI chr12:1,020,556...1,050,568
Ensembl chr12:1,019,263...1,050,231 		JBrowse link
G GRIN2A glutamate ionotropic receptor NMDA type subunit 2A ISO SMPDB SMP:00671 NCBI chr 5:9,233,028...9,707,322
Ensembl chr 5:9,286,775...9,462,828 		JBrowse link
G GRIN3A glutamate ionotropic receptor NMDA type subunit 3A ISO SMPDB SMP:00671 NCBI chr12:37,700,311...37,865,390
Ensembl chr12:37,701,039...37,867,041 		JBrowse link
G HTR1A 5-hydroxytryptamine receptor 1A ISO SMPDB SMP:00671 NCBI chr 4:60,159,542...60,162,947
Ensembl chr 4:60,159,944...60,161,212 		JBrowse link
G KCND2 potassium voltage-gated channel subfamily D member 2 ISO SMPDB SMP:00671 NCBI chr21:89,091,939...89,575,464 JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 ISO SMPDB SMP:00671 NCBI chr 9:94,854,024...94,873,655
Ensembl chr 9:94,855,403...94,873,312 		JBrowse link
G OPRM1 opioid receptor mu 1 ISO SMPDB SMP:00671 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PCSK2 proprotein convertase subtilisin/kexin type 2 ISO SMPDB SMP:00671 NCBI chr 2:46,293,983...46,548,902
Ensembl chr 2:46,294,005...46,549,609 		JBrowse link
G POMC proopiomelanocortin ISO SMPDB SMP:00671 NCBI chr14:82,491,296...82,499,289
Ensembl chr14:82,494,323...82,499,447 		JBrowse link
G SCN10A sodium voltage-gated channel alpha subunit 10 ISO SMPDB SMP:00671 NCBI chr15:624,962...724,018
Ensembl chr15:625,742...721,963 		JBrowse link
G SCN1B sodium voltage-gated channel beta subunit 1 ISO SMPDB SMP:00671 NCBI chr 6:29,962,993...29,972,845
Ensembl chr 6:29,962,843...29,973,325 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 ISO SMPDB SMP:00671 NCBI chr 5:41,434,004...41,482,568
Ensembl chr 5:41,435,387...41,483,643 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO SMPDB SMP:00671 NCBI chr 4:1,209,013...1,258,797
Ensembl chr 4:1,209,019...1,258,866 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 ISO SMPDB SMP:00671 NCBI chr16:23,929,196...23,969,665
Ensembl chr16:23,927,311...23,955,616 		JBrowse link
tramadol pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC2 ATP binding cassette subfamily C member 2 ISO SMPDB SMP:00637 NCBI chr 9:92,826,423...92,902,389
Ensembl chr 9:92,841,818...92,902,265 		JBrowse link
G CYP2B6 cytochrome P450 family 2 subfamily B member 6 ISO SMPDB SMP:00637 NCBI chr 6:35,392,699...35,418,171
Ensembl chr 6:35,393,342...35,418,106 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 ISO SMPDB SMP:00637 NCBI chr19:24,667,207...24,672,580
Ensembl chr19:24,667,282...24,671,513 		JBrowse link
G LOC103246766 cytochrome P450 3A8 ISO SMPDB SMP:00637 NCBI chr28:13,297,566...13,330,023 JBrowse link
G SLC22A1 solute carrier family 22 member 1 ISO SMPDB SMP:00637 NCBI chr13:87,744,600...87,780,846
Ensembl chr13:87,745,023...87,781,073 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4027
    drug pathway 383
      nervous system drug pathway 173
        analgesic and/or antipyretic drug pathway 89
          acetylsalicylic acid drug pathway + 26
          antipyrine drug pathway + 26
          diflunisal drug pathway + 26
          ibuprofen drug pathway + 41
          indometacin drug pathway + 27
          ketoprofen drug pathway + 26
          lornoxicam drug pathway + 26
          magnesium salicylate drug pathway + 26
          naproxen drug pathway + 26
          opioid drug pathway + 50
          paracetamol drug pathway + 50
          salicylic acid drug pathway + 26
          sodium salicylate drug pathway + 26
paths to the root