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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:catecholamine metabolic pathway
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Accession:PW:0000443 term browser browse the term
Definition:Those metabolic reactions involved in the synthesis, utilization and/or degradation of catecholamines - chemical compounds derived from tyrosine. Epinephrine, norepinephrine and dopamine are among the most abundant and are produced primarily from the adrenal medulla and the postganglionic fibers of the sympathetic nervous system.
Synonyms:related_synonym: catecholamine metabolic process


show annotations for term's descendants           Sort by:
catecholamine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO SMPDB SMP:00012 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130 		JBrowse link
G DDC dopa decarboxylase ISO SMPDB SMP:00012 NCBI chr18:1,802,239...1,876,714
Ensembl chr18:1,803,273...1,867,616 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO SMPDB SMP:00012 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551 		JBrowse link
G TH tyrosine hydroxylase ISO SMPDB SMP:00012 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
dopamine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDC dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:1,802,239...1,876,714
Ensembl chr18:1,803,273...1,867,616 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:62,970,850...62,987,512
Ensembl chr 3:62,970,121...63,028,395 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 ISO RGD PMID:19903816 RGD:5128868 NCBI chr28:27,731,709...27,809,341
Ensembl chr28:27,731,004...27,767,993 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
epinephrine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130 		JBrowse link
G DDC dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:1,802,239...1,876,714
Ensembl chr18:1,803,273...1,867,616 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase ISO RGD PMID:7914070 PMID:19342614 RGD:4139902 RGD:4139904 NCBI chr 9:22,808,505...22,810,587
Ensembl chr 9:22,808,601...22,810,551 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:62,970,850...62,987,512
Ensembl chr 3:62,970,121...63,028,395 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 ISO RGD PMID:19903816 RGD:5128868 NCBI chr28:27,731,709...27,809,341
Ensembl chr28:27,731,004...27,767,993 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
norepinephrine biosynthetic pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DBH dopamine beta-hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 9:50,004,806...50,024,130
Ensembl chr 9:50,004,806...50,024,130 		JBrowse link
G DDC dopa decarboxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:1,802,239...1,876,714
Ensembl chr18:1,803,273...1,867,616 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO RGD PMID:19342614 RGD:4139904 NCBI chr 3:62,970,850...62,987,512
Ensembl chr 3:62,970,121...63,028,395 		JBrowse link
G SLC18A2 solute carrier family 18 member A2 ISO RGD PMID:19903816 RGD:5128868 NCBI chr28:27,731,709...27,809,341
Ensembl chr28:27,731,004...27,767,993 		JBrowse link
G TH tyrosine hydroxylase ISO RGD PMID:19342614 RGD:4139904 NCBI chr18:46,327,136...46,334,973
Ensembl chr18:46,327,137...46,335,602 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4045
    classic metabolic pathway 1010
      biogenic amines and polyamines metabolic pathway 28
        catecholamine metabolic pathway 6
          catecholamine biosynthetic pathway + 6
          catecholamine degradation pathway + 0
          dopamine metabolic pathway + 4
          epinephrine metabolic pathway + 6
          norepinephrine metabolic pathway + 5
Path 2
Term Annotations click to browse term
  pathway 4045
    classic metabolic pathway 1010
      metabolic pathway pertinent to the brain 92
        neurotransmitter metabolic pathway 34
          amine neurotransmitter metabolic pathway 8
            catecholamine metabolic pathway 6
              catecholamine biosynthetic pathway + 6
              catecholamine degradation pathway + 0
              dopamine metabolic pathway + 4
              epinephrine metabolic pathway + 6
              norepinephrine metabolic pathway + 5
paths to the root