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MAMMALIAN PHENOTYPE - ANNOTATIONS

The Mouse Adult Gross Anatomy Ontology and Mammalian Phenotype Ontology are downloaded weekly from the Mouse Genome Informatics databases at Jackson Laboratories (ftp://ftp.informatics.jax.org/pub/reports/index.html). For more information about these ontologies, see the MGI Publications Page at http://www.informatics.jax.org/mgihome/other/publications.shtml.
Term:decreased alveolar macrophage number
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Accession:MP:0014229 term browser browse the term
Definition:reduction in the number of round, granular, mononuclear phagocytes found in the alveoli of the lungs which ingest small inhaled particles resulting in degradation and presentation of the antigen to immunocompetent cells
Synonyms:exact_synonym: alveolar macrophage hypoplasia;   reduced alveolar macrophage number


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decreased alveolar macrophage number term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il36g interleukin 36G IAGP MGI PMID:29848754 NCBI chr 2:24,076,488...24,083,579
Ensembl chr 2:24,076,488...24,083,580 		JBrowse link
G Lyz2 lysozyme 2 IAGP MGI PMID:28533230 NCBI chr10:117,113,446...117,118,177
Ensembl chr10:117,113,236...117,118,226 		JBrowse link
G Pikfyve phosphoinositide kinase, FYVE type zinc finger containing IAGP MGI PMID:28533230 NCBI chr 1:65,225,796...65,317,855
Ensembl chr 1:65,225,842...65,317,854 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  mammalian phenotype 16762
    respiratory system phenotype 1843
      abnormal respiratory system morphology 1272
        abnormal lung morphology 828
          abnormal pulmonary alveolar system morphology 376
            abnormal pulmonary alveolar parenchyma morphology 115
              abnormal alveolar macrophage morphology 20
                abnormal alveolar macrophage number 5
                  decreased alveolar macrophage number 3
Path 2
Term Annotations click to browse term
  mammalian phenotype 16762
    immune system phenotype 5628
      abnormal immune system morphology 4021
        abnormal immune system cell morphology 2809
          abnormal leukocyte morphology 2788
            abnormal myeloid leukocyte morphology 1445
              abnormal phagocyte morphology 1200
                abnormal mononuclear phagocyte morphology 859
                  abnormal macrophage morphology 583
                    abnormal macrophage cell number 365
                      abnormal alveolar macrophage number 5
                        decreased alveolar macrophage number 3
paths to the root