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MEASUREMENT METHODS - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:automated plasma alanine aminotransferase activity assay
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Accession:MMO:0000808 term browser browse the term
Definition:This is a method using a device designed to follow a predetermined sequence of individual operations repeatedly and essentially without external influence or control to measure the enzymatic activity of glutamic-pyruvate transaminase enzyme, commonly known as alanine transaminase or alanine aminotransferase (ALT), enzyme in a specified sample of plasma, the fluid portion of the blood remaining after cells and platelets are removed. ALT catalyzes the reversible transamination between alanine and 2-oxoglutarate to generate pyruvate and glutamate. Serum ALT level is used as an enzymatic marker for liver disease or damage.
Synonyms:exact_synonym: automated plasma ALT activity assay;   automated plasma GPT activity assay;   automated plasma alanine aminotransferase activity test;   automated plasma alanine transaminase activity assay;   automated plasma glutamic-pyruvate transaminase activity assay


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Related Phenotype Data for Term "automated plasma alanine aminotransferase activity assay" (MMO:0000808)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  measurement method 2368
    ex vivo method 1236
      enzyme or transport activity assay 3
        blood enzyme activity assay 3
          blood alanine aminotransferase activity assay 0
            plasma alanine aminotransferase activity assay 0
              automated plasma alanine aminotransferase activity assay 0
Path 2
Term Annotations click to browse term
  measurement method 2368
    ex vivo method 1236
      ex vivo biological fluid analysis 305
        ex vivo blood analysis 250
          blood protein analysis 11
            blood enzyme activity assay 3
              blood alanine aminotransferase activity assay 0
                plasma alanine aminotransferase activity assay 0
                  automated plasma alanine aminotransferase activity assay 0
paths to the root