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HUMAN PHENOTYPE - ANNOTATIONS

The Human Phenotype Ontology (HPO) is downloaded weekly from http://compbio.charite.de/hudson/job/hpo/lastStableBuild/artifact/ontology/release/hp.obo. The file downloaded is considered the "last stable build" available for the ontology. For more about the HPO, view their website at http://www.human-phenotype-ontology.org/.
Term:Abnormality of B cell physiology
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Accession:HP:0005372 term browser browse the term
Definition:An abnormality of the physiological functioning of B cells.
Comment:This term refers to any abnormality of the B cells, which play a role in the humoral immune response. The main functions of B cells are to produce antibodies, to perform the role of antigen presenting cells, and to develop into memory cells.
Synonyms:exact_synonym: Reduced B cell function
 alt_id: HP:0005398
 xref: UMLS:C1849242


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Term paths to the root
Path 1
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of metabolism/homeostasis 0
        Abnormal cellular physiology 0
          Abnormal lymphocyte physiology 0
            Abnormality of B cell physiology 0
              Abnormal immunoglobulin level + 0
              Abnormal immunoglobulin level in body fluid + 0
              Defective B cell activation + 0
              Impaired Ig class switch recombination 0
              Impaired memory B cell generation 0
Path 2
Term Annotations click to browse term
  Human phenotype 0
    Phenotypic abnormality 0
      Abnormality of the immune system 0
        Abnormality of immune system physiology 0
          Abnormal leukocyte physiology 0
            Abnormal lymphocyte physiology 0
              Abnormality of B cell physiology 0
                Abnormal immunoglobulin level + 0
                Abnormal immunoglobulin level in body fluid + 0
                Defective B cell activation + 0
                Impaired Ig class switch recombination 0
                Impaired memory B cell generation 0
paths to the root