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Pathways
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ONTOLOGY REPORT - ANNOTATIONS

Term:lipoxygenase pathway
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Accession:GO:0019372 term browser browse the term
Definition:The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.


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lipoxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12 arachidonate 12-lipoxygenase, 12S type involved_in ISO
IDA
IBA
IEA		 (PMID:8319693)
PMID:23382512
(MGI:1202206|PMID:9501222), (MGI:66203|PMID:8188678)
GO_REF:0000033
GO_REF:0000118		 RGD
GO_Central
TreeGrafter		 PMID:8188678 PMID:8319693 PMID:9501222 PMID:23382512 GO_REF:0000033 GO_REF:0000118 MGI:1202206 MGI:66203, RGD:8554649 NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542 		JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in IEA
ISS
ISO
IBA		 GO_REF:0000107
GO_REF:0000024
(PMID:15629692), (PMID:21558561)
GO_REF:0000033
GO_REF:0000118		 Ensembl
UniProt
RGD
GO_Central
TreeGrafter		 PMID:15629692 PMID:21558561 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr10:53,863,060...53,874,938
Ensembl chr10:53,863,060...53,874,938 		JBrowse link
G Alox12e arachidonate 12-lipoxygenase, epidermal involved_in IDA
IEA
IBA		 PMID:23382512
GO_REF:0000107
GO_REF:0000033
GO_REF:0000118		 Ensembl
GO_Central
TreeGrafter		 PMID:23382512 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118, RGD:8554649 NCBI chr10:55,034,392...55,041,857
Ensembl chr10:55,034,392...55,041,928 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in IDA
ISO
IEA
IBA		 (PMID:1944593), (PMID:23242647)
(MGI:1101294|PMID:8798642), (MGI:66203|PMID:8188678)
(PMID:8305485)
GO_REF:0000117
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:1944593 PMID:8188678 PMID:8305485 PMID:8798642 PMID:23242647 More... GO_REF:0000033 GO_REF:0000117 MGI:1101294 MGI:66203, RGD:70288 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
G Alox15b arachidonate 15-lipoxygenase, type B involved_in IDA
IEA
ISO
IBA		 PMID:23382512
GO_REF:0000107
(MGI:1097306|PMID:9305900)
GO_REF:0000118
GO_REF:0000033		 Ensembl
RGD
TreeGrafter
GO_Central		 PMID:9305900 PMID:23382512 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 MGI:1097306, RGD:8554649 NCBI chr10:53,892,496...53,901,812
Ensembl chr10:53,892,466...53,901,812 		JBrowse link
G Alox5 arachidonate 5-lipoxygenase involved_in IEA
IBA		 GO_REF:0000118
GO_REF:0000033		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743 		JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein IMP
IDA		 RGD PMID:18945963 PMID:17517102 RGD:2313900, RGD:2313910 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISS
ISO
IBA		 GO_REF:0000024
(PMID:20921226)
GO_REF:0000033		 UniProt
RGD
GO_Central		 PMID:20921226 GO_REF:0000024 GO_REF:0000033 NCBI chr10:53,830,219...53,854,328
Ensembl chr10:53,831,264...53,854,328 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO
ISS
IEA		 (PMID:11115402)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:11115402 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO
ISS		 (PMID:11115402)
GO_REF:0000024		 RGD
UniProt		 PMID:11115402 GO_REF:0000024 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Pla2g3 phospholipase A2, group III acts_upstream_of_or_within ISO MGI:4461174 (PMID:20424323) RGD PMID:20424323 NCBI chr14:78,367,625...78,373,913
Ensembl chr14:78,368,105...78,373,913 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular metabolic process 9901
        cellular lipid metabolic process 1106
          fatty acid metabolic process 467
            lipoxygenase pathway 11
              green leaf volatile biosynthetic process 0
Path 2
Term Annotations click to browse term
  biological_process 20413
    cellular process 18812
      cellular metabolic process 9901
        organic acid metabolic process 1077
          oxoacid metabolic process 1059
            carboxylic acid metabolic process 1040
              monocarboxylic acid metabolic process 770
                fatty acid metabolic process 467
                  lipoxygenase pathway 11
                    green leaf volatile biosynthetic process 0
paths to the root