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ONTOLOGY REPORT - ANNOTATIONS
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Term:
positive regulation of microglial cell mediated cytotoxicity
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Accession:
GO:1904151
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Definition:
Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.
Synonyms:
exact_synonym:
up regulation of microglial cell mediated cytotoxicity; upregulation of microglial cell mediated cytotoxicity
narrow_synonym:
activation of microglial cell mediated cytotoxicity
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Genes (4)
positive regulation of microglial cell mediated cytotoxicity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
Itgam
integrin subunit alpha M
involved_in
ISO
(MGI:3812233|PMID:18685038)
UniProt
PMID:18685038
MGI:3812233
NCBI chrNW_004624782:14,316,505...14,367,841
Ensembl chrNW_004624782:14,318,499...14,367,922
G
Spi1
Spi-1 proto-oncogene
involved_in
ISO
(MGI:6093262|PMID:28628103)
ARUK-UCL
PMID:28628103
MGI:6093262
NCBI chrNW_004624767:1,376,649...1,404,382
Ensembl chrNW_004624767:1,394,704...1,404,406
G
Stap1
signal transducing adaptor family member 1
involved_in
ISO
(MGI:3831067|PMID:19100238)
BHF-UCL
PMID:19100238
MGI:3831067
NCBI chrNW_004624761:1,361,271...1,409,548
Ensembl chrNW_004624761:1,361,498...1,409,674
G
Tyrobp
transmembrane immune signaling adaptor TYROBP
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chrNW_004624794:10,183,934...10,187,180
Ensembl chrNW_004624794:10,183,515...10,187,244
Term paths to the root
one shortest
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Path 1
Term
Annotations
biological_process
15093
cellular process
14253
cell killing
141
leukocyte mediated cytotoxicity
98
positive regulation of leukocyte mediated cytotoxicity
40
positive regulation of microglial cell mediated cytotoxicity
4
Path 2
Term
Annotations
biological_process
15093
biological regulation
10618
regulation of biological process
10301
regulation of immune system process
1351
positive regulation of immune system process
948
positive regulation of immune effector process
234
positive regulation of leukocyte mediated immunity
124
positive regulation of leukocyte mediated cytotoxicity
40
positive regulation of microglial cell mediated cytotoxicity
4