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ONTOLOGY REPORT - ANNOTATIONS

Term:amylin receptor complex 3
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Accession:GO:0150058 term browser browse the term
Definition:A G protein-coupled receptor complex that serves as a receptor for amylin polypeptide (AMY) and consists of a calcitonin receptor (CTR/CALCR) and a receptor activity-modifying protein (RAMP) 3. Amylin receptor complex 3 (AMY3) also serves as a receptor for the amyloid-beta complex. Ligand binding to AMY3 results in increased cytosolic calcium ion levels and in activation on multiple intracellular signaling pathways.
Synonyms:exact_synonym: AMY3 complex


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amylin receptor complex 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCR calcitonin receptor part_of IDA (PMID:22500019) ARUK-UCL PMID:22500019 NCBI chr 7:93,424,486...93,574,724
Ensembl chr 7:93,424,486...93,574,730 		JBrowse link
G RAMP3 receptor activity modifying protein 3 part_of IDA (PMID:22500019) ARUK-UCL PMID:22500019 NCBI chr 7:45,157,791...45,184,250
Ensembl chr 7:45,157,791...45,186,302 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20718
    protein-containing complex 7461
      receptor complex 565
        plasma membrane signaling receptor complex 338
          G protein-coupled receptor complex 13
            calcitonin family receptor complex 5
              amylin receptor complex 2
                amylin receptor complex 3 2
Path 2
Term Annotations click to browse term
  cellular_component 20718
    cellular anatomical entity 20332
      cell periphery 6720
        plasma membrane 6204
          plasma membrane protein complex 776
            plasma membrane signaling receptor complex 338
              G protein-coupled receptor complex 13
                calcitonin family receptor complex 5
                  amylin receptor complex 2
                    amylin receptor complex 3 2
paths to the root