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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of actin nucleation
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Accession:GO:0051126 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
Synonyms:exact_synonym: down regulation of actin nucleation;   downregulation of actin nucleation
 narrow_synonym: inhibition of actin nucleation


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negative regulation of actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arpin actin-related protein 2/3 complex inhibitor involved_in ISO
IBA		 (PMID:24132237)
GO_REF:0000033		 RGD
GO_Central		 PMID:24132237 GO_REF:0000033 NCBI chr 1:133,864,288...133,873,124
Ensembl chr 1:133,864,265...133,873,124 		JBrowse link
G Coro1a coronin 1A involved_in ISO (PMID:17442961) RGD PMID:17442961 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534 		JBrowse link
negative regulation of Arp2/3 complex-mediated actin nucleation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Coro1b coronin 1B involved_in IEA
ISO		 GO_REF:0000107
(PMID:17350576), (PMID:18775315)		 Ensembl
RGD		 PMID:17350576 PMID:18775315 GO_REF:0000107 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Ctnna2 catenin alpha 2 involved_in ISO (PMID:30013181) RGD PMID:30013181 NCBI chr 4:109,294,249...110,443,409
Ensembl chr 4:109,293,978...110,443,522 		JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 involved_in ISO (PMID:32128961) RGD PMID:32128961 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173 		JBrowse link
G Gmfb glia maturation factor, beta involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gmfg glia maturation factor, gamma involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 GO_REF:0000107
(PMID:23727094)
GO_REF:0000033		 Ensembl
RGD
GO_Central		 PMID:23727094 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:83,728,797...83,739,189
Ensembl chr 1:83,728,776...83,739,183 		JBrowse link
G Hip1r huntingtin interacting protein 1 related involved_in ISO (MGI:5805366|PMID:17318189) RGD PMID:17318189 MGI:5805366 NCBI chr12:32,590,164...32,618,841
Ensembl chr12:32,590,165...32,618,734 		JBrowse link
G Pick1 protein interacting with PRKCA 1 involved_in IDA PMID:18297063 UniProt PMID:18297063 RGD:8554748 NCBI chr 7:110,796,623...110,816,850
Ensembl chr 7:110,797,117...110,816,848 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      negative regulation of cellular process 5280
        negative regulation of cellular component organization 794
          negative regulation of supramolecular fiber organization 190
            negative regulation of actin nucleation 9
              negative regulation of Arp2/3 complex-mediated actin nucleation 7
Path 2
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      cellular component organization or biogenesis 6956
        cellular component organization 6692
          organelle organization 3681
            cytoskeleton organization 1530
              regulation of cytoskeleton organization 546
                regulation of actin cytoskeleton organization 366
                  regulation of actin filament organization 289
                    regulation of actin nucleation 34
                      negative regulation of actin nucleation 9
                        negative regulation of Arp2/3 complex-mediated actin nucleation 7
paths to the root