Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

ONTOLOGY REPORT - ANNOTATIONS

Term:ESC/E(Z) complex
go back to main search page
Accession:GO:0035098 term browser browse the term
Definition:A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
Synonyms:exact_synonym: Extra Sex Combs/Enhancer of Zeste complex;   PRC2 complex

GViewer not supported for the selected species.

show annotations for term's descendants           Sort by:
ESC/E(Z) complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aebp2 AE binding protein 2 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936548:6,828,190...6,890,287
Ensembl chrNW_004936548:6,810,002...6,889,614 		JBrowse link
G Dnmt3l DNA methyltransferase 3 like part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936500:143,078...160,318
Ensembl chrNW_004936500:143,078...160,212 		JBrowse link
G Eed embryonic ectoderm development part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936498:14,050,731...14,082,410
Ensembl chrNW_004936498:14,051,045...14,083,570 		JBrowse link
G Epop elongin BC and polycomb repressive complex 2 associated protein part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:14,086,278...14,088,746
Ensembl chrNW_004936490:14,087,171...14,088,310 		JBrowse link
G Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936490:17,430,383...17,465,889
Ensembl chrNW_004936490:17,428,677...17,465,877 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936527:5,024,077...5,069,152
Ensembl chrNW_004936527:5,024,068...5,063,939 		JBrowse link
G Hdac2 histone deacetylase 2 part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936679:2,448,676...2,474,641
Ensembl chrNW_004936679:2,448,390...2,474,641 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936552:1,566,382...1,786,837
Ensembl chrNW_004936552:1,566,788...1,785,490 		JBrowse link
G Mtf2 metal response element binding transcription factor 2 part_of IEA Ensembl GO_REF:0000107 NCBI chrNW_004936537:6,071,435...6,134,144
Ensembl chrNW_004936537:6,071,153...6,134,144 		JBrowse link
G Phf1 PHD finger protein 1 part_of
located_in		 IEA
ISO		 (PMID:23273982) Ensembl
UniProt		 PMID:23273982 GO_REF:0000107 NCBI chrNW_004936476:25,481,938...25,487,026
Ensembl chrNW_004936476:25,479,953...25,487,403 		JBrowse link
G Phf19 PHD finger protein 19 part_of
located_in		 IEA
ISO		 (PMID:23104054) Ensembl
UniProt		 PMID:23104054 GO_REF:0000107 NCBI chrNW_004936487:9,310,327...9,326,650
Ensembl chrNW_004936487:9,310,790...9,326,681 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:15,592,226...15,611,381
Ensembl chrNW_004936474:15,592,240...15,611,381 		JBrowse link
G Rbbp7 RB binding protein 7, chromatin remodeling factor part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936470:6,107,754...6,133,136
Ensembl chrNW_004936470:6,104,510...6,133,185 		JBrowse link
G Sirt1 sirtuin 1 part_of
located_in		 IEA
ISO		 (PMID:15684044) Ensembl
UniProt		 PMID:15684044 GO_REF:0000107 NCBI chrNW_004936521:10,296,097...10,316,673
Ensembl chrNW_004936521:10,296,097...10,322,215 		JBrowse link
G Suz12 SUZ12 polycomb repressive complex 2 subunit part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936538:2,921,987...2,971,521
Ensembl chrNW_004936538:2,921,719...2,971,552 		JBrowse link
G Trim37 tripartite motif containing 37 part_of
located_in		 IEA
ISO		 (PMID:25470042) Ensembl
UniProt		 PMID:25470042 GO_REF:0000107 NCBI chrNW_004936490:4,163,871...4,310,016
Ensembl chrNW_004936490:4,163,719...4,354,932 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 16770
    protein-containing complex 5551
      nuclear protein-containing complex 1213
        PcG protein complex 60
          ESC/E(Z) complex 16
Path 2
Term Annotations click to browse term
  cellular_component 16770
    cellular anatomical entity 16679
      organelle 11991
        membrane-bounded organelle 10951
          intracellular membrane-bounded organelle 10436
            nucleus 6468
              nuclear lumen 3793
                nucleoplasm 3364
                  histone methyltransferase complex 69
                    ESC/E(Z) complex 16
paths to the root