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ONTOLOGY REPORT - ANNOTATIONS

Term:vacuolar proton-transporting V-type ATPase complex
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Accession:GO:0016471 term browser browse the term
Definition:A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
Comment:See also the cellular component terms 'vacuolar proton-transporting V-type ATPase, V1 domain ; GO:0000221' and 'vacuolar proton-transporting V-type ATPase, V0 domain ; GO:0000220' and the molecular function term 'hydrogen ion transporting ATPase activity, rotational mechanism ; GO:0046961'.
Synonyms:exact_synonym: vacuolar hydrogen-translocating V-type ATPase complex


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vacuolar proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6AP2 ATPase H+ transporting accessory protein 2 part_of IEA Ensembl GO_REF:0000107 NCBI chr  X:33,026,525...33,052,252
Ensembl chr  X:40,730,677...40,756,209 		JBrowse link
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr17:14,793,717...14,857,706
Ensembl chr17:15,017,695...15,082,470 		JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr12:121,297,959...121,343,294
Ensembl chr12:125,522,886...125,569,858 		JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:130,665,997...130,758,537
Ensembl chr 7:143,154,712...143,218,802 		JBrowse link
G ATP6V0D1 ATPase H+ transporting V0 subunit d1 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr16:47,783,327...47,826,138
Ensembl chr16:67,171,883...67,214,670 		JBrowse link
G ATP6V0D2 ATPase H+ transporting V0 subunit d2 part_of IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:82,800,353...82,855,741
Ensembl chr 8:84,771,427...84,826,406 		JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 part_of IEA Ensembl GO_REF:0000107 NCBI chr2A:71,000,096...71,030,306
Ensembl chr2A:72,113,859...72,143,612 		JBrowse link
G ATP6V1F ATPase H+ transporting V1 subunit F part_of ISO (PMID:18752060) UniProt PMID:18752060 NCBI chr 7:120,814,560...120,817,612
Ensembl chr 7:133,339,284...133,342,423 		JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 part_of IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 9:85,685,910...85,696,255
Ensembl chr 9:114,048,387...114,058,878 		JBrowse link
G ATP6V1G2 ATPase H+ transporting V1 subunit G2 part_of IEA Ensembl
TreeGrafter
InterPro		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000118 NCBI chr 6:31,205,541...31,207,930
Ensembl chr 6:32,095,462...32,097,835 		JBrowse link
G ATP6V1G3 ATPase H+ transporting V1 subunit G3 part_of IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr 1:174,130,976...174,148,524
Ensembl chr 1:178,440,516...178,458,108 		JBrowse link
G CCDC115 coiled-coil domain containing 115 part_of ISO (PMID:28296633) UniProt PMID:28296633 NCBI chr2B:28,624,800...28,629,543 JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr11:63,120,913...63,132,831
Ensembl chr11:66,429,435...66,441,327 		JBrowse link
G TMEM199 transmembrane protein 199 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:28,412,229...28,416,840
Ensembl chr17:28,914,604...28,919,194 		JBrowse link
lysosomal proton-transporting V-type ATPase complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPAAR small regulatory polypeptide of amino acid response located_in
part_of		 ISO
IEA		 (PMID:28024296) UniProt
Ensembl		 PMID:28024296 GO_REF:0000107
vacuolar proton-transporting V-type ATPase, V0 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V0A1 ATPase H+ transporting V0 subunit a1 part_of IEA InterPro GO_REF:0000002 NCBI chr17:14,793,717...14,857,706
Ensembl chr17:15,017,695...15,082,470 		JBrowse link
G ATP6V0A2 ATPase H+ transporting V0 subunit a2 part_of IEA InterPro GO_REF:0000002 NCBI chr12:121,297,959...121,343,294
Ensembl chr12:125,522,886...125,569,858 		JBrowse link
G ATP6V0A4 ATPase H+ transporting V0 subunit a4 part_of IEA InterPro GO_REF:0000002 NCBI chr 7:130,665,997...130,758,537
Ensembl chr 7:143,154,712...143,218,802 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 part_of IEA InterPro GO_REF:0000002 NCBI chr11:63,120,913...63,132,831
Ensembl chr11:66,429,435...66,441,327 		JBrowse link
vacuolar proton-transporting V-type ATPase, V1 domain term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP6V1A ATPase H+ transporting V1 subunit A part_of IEA Ensembl GO_REF:0000107 NCBI chr 3:110,888,504...110,951,750
Ensembl chr 3:117,808,963...117,872,349 		JBrowse link
G ATP6V1B1 ATPase H+ transporting V1 subunit B1 part_of IEA Ensembl GO_REF:0000107 NCBI chr2A:71,000,096...71,030,306
Ensembl chr2A:72,113,859...72,143,612 		JBrowse link
G ATP6V1B2 ATPase H+ transporting V1 subunit B2 part_of IEA Ensembl GO_REF:0000107 NCBI chr 8:19,422,423...19,446,799
Ensembl chr 8:16,369,937...16,394,284 		JBrowse link
G ATP6V1C1 ATPase H+ transporting V1 subunit C1 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr 8:99,521,146...99,725,603
Ensembl chr 8:101,832,538...101,883,956 		JBrowse link
G ATP6V1C2 ATPase H+ transporting V1 subunit C2 part_of IEA TreeGrafter GO_REF:0000118 NCBI chr2A:10,689,538...10,783,372
Ensembl chr2A:10,872,071...10,936,457 		JBrowse link
G ATP6V1E1 ATPase H+ transporting V1 subunit E1 part_of IEA Ensembl GO_REF:0000107 NCBI chr22:1,023,028...1,059,416
Ensembl chr22:16,452,358...16,486,902 		JBrowse link
G ATP6V1G1 ATPase H+ transporting V1 subunit G1 part_of IEA Ensembl GO_REF:0000107 NCBI chr 9:85,685,910...85,696,255
Ensembl chr 9:114,048,387...114,058,878 		JBrowse link
G ATP6V1H ATPase H+ transporting V1 subunit H part_of IEA UniProt
InterPro		 GO_REF:0000002 GO_REF:0000104 NCBI chr 8:50,152,664...50,269,290
Ensembl chr 8:47,528,972...47,647,588 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17180
    protein-containing complex 5908
      membrane protein complex 1248
        proton-transporting two-sector ATPase complex 54
          proton-transporting V-type ATPase complex 27
            vacuolar proton-transporting V-type ATPase complex 21
              lysosomal proton-transporting V-type ATPase complex + 1
              vacuolar proton-transporting V-type ATPase, V0 domain + 4
              vacuolar proton-transporting V-type ATPase, V1 domain + 8
Path 2
Term Annotations click to browse term
  cellular_component 17180
    cellular anatomical entity 16967
      organelle 12496
        intracellular organelle 12077
          intracellular membrane-bounded organelle 10862
            vacuole 590
              vacuolar membrane 307
                vacuolar proton-transporting V-type ATPase complex 21
                  lysosomal proton-transporting V-type ATPase complex + 1
                  vacuolar proton-transporting V-type ATPase, V0 domain + 4
                  vacuolar proton-transporting V-type ATPase, V1 domain + 8
paths to the root