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ONTOLOGY REPORT - ANNOTATIONS

Term:high voltage-gated calcium channel activity
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Accession:GO:0008331 term browser browse the term
Definition:Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: high voltage-dependent calcium channel activity
 related_synonym: L-type calcium channel;   N-type calcium channel;   P-type calcium channel;   Q-type calcium channel


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high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:17068255 PMID:21611731 GO_REF:0000107 GO_REF:0000118 RGD:7205477 RGD:7205480 NCBI chr20:48,747,087...49,036,627
Ensembl chr20:48,821,025...49,036,032 		JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO
IEA		 RGD
TreeGrafter		 PMID:18701069 GO_REF:0000118 RGD:7205441 NCBI chr 9:47,813,625...48,009,532
Ensembl chr 9:47,816,393...48,009,406 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO
IEA		 RGD
TreeGrafter		 PMID:17068255 GO_REF:0000118 RGD:7205477 NCBI chr27:44,007,363...44,748,251
Ensembl chr27:44,008,020...44,746,429 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
RGD
Ensembl
TreeGrafter		 PMID:1309651 PMID:18322004 GO_REF:0000107 GO_REF:0000118 RGD:7207845 NCBI chr20:36,189,986...36,488,460
Ensembl chr20:36,191,810...36,613,686 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables IEA TreeGrafter GO_REF:0000118 NCBI chr 7:14,892,165...15,267,418
Ensembl chr 7:14,707,801...15,267,422 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables IEA TreeGrafter GO_REF:0000118 NCBI chr  X:42,302,971...42,327,787
Ensembl chr  X:42,303,158...42,326,774 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables ISO
IEA		 RGD
Ensembl
TreeGrafter		 PMID:7479909 GO_REF:0000107 GO_REF:0000118 RGD:634679 NCBI chr 7:2,108,716...2,172,246
Ensembl chr 7:2,108,455...2,303,220 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 enables ISO (PMID:11756409) MGI PMID:11756409 NCBI chr 9:23,182,407...23,197,035
Ensembl chr 9:23,180,554...23,195,673 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
Ensembl		 PMID:1309651 GO_REF:0000107 NCBI chr 2:18,537,100...18,787,728
Ensembl chr 2:18,538,620...18,902,286 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 contributes_to ISO PMID:25527503 BHF-UCL PMID:25527503 RGD:11059598 NCBI chr27:5,705,587...5,714,620
Ensembl chr27:5,706,064...5,717,647 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 contributes_to
enables		 ISO
IEA		 (PMID:11880487) UniProtKB
Ensembl		 PMID:11880487 GO_REF:0000107 NCBI chr19:52,987,170...53,116,410
Ensembl chr19:52,993,618...53,116,140
Ensembl chr19:52,993,618...53,116,140 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        monoatomic ion transmembrane transporter activity 768
          monoatomic ion channel activity 468
            monoatomic cation channel activity 360
              calcium channel activity 128
                voltage-gated calcium channel activity 44
                  high voltage-gated calcium channel activity 11
Path 2
Term Annotations click to browse term
  molecular_function 18798
    transporter activity 1259
      transmembrane transporter activity 1169
        passive transmembrane transporter activity 533
          channel activity 533
            gated channel activity 333
              voltage-gated channel activity 183
                voltage-gated monoatomic ion channel activity 180
                  voltage-gated monoatomic cation channel activity 150
                    voltage-gated calcium channel activity 44
                      high voltage-gated calcium channel activity 11
paths to the root