ONTOLOGY REPORT - ANNOTATIONS
Term: homologous chromosome pairing at meiosis
Accession: GO:0007129
browse the term
Definition: The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Homologous chromosome pairing begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
Synonyms: narrow_synonym: chromosomal synapsis; synapsis
related_synonym: chromosomal pairing
xref: Wikipedia:Synapsis
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ANKRD31
ankyrin repeat domain 31
involved_in
ISO
(MGI:6316415|PMID:31003867), (MGI:6316551|PMID:31000436)
UniProt
PMID:31000436 PMID:31003867
MGI:6316415 MGI:6316551
NCBI chr 5:40,060,599...40,236,468
Ensembl chr 5:40,673,567...40,849,519
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BRIP1
BRCA1 interacting helicase 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:26490168)
Ensembl MGI
PMID:26490168
GO_REF:0000107
NCBI chr17:55,786,568...55,973,366
Ensembl chr17:60,901,073...61,083,462
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C15H14orf39
chromosome 15 C14orf39 homolog
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr14:41,040,315...41,090,267
Ensembl chr14:59,304,040...59,351,956
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CCNE1
cyclin E1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24586195)
Ensembl MGI
PMID:24586195
GO_REF:0000107
NCBI chr19:26,739,285...26,751,630
Ensembl chr19:35,496,700...35,510,295
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CCNE2
cyclin E2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24586195)
Ensembl MGI
PMID:24586195
GO_REF:0000107
NCBI chr 8:91,499,647...91,518,488
Ensembl chr 8:93,702,104...93,717,151
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DMC1
DNA meiotic recombinase 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17696610)
Ensembl MGI
PMID:17696610
GO_REF:0000107
NCBI chr22:19,433,989...19,485,804
Ensembl chr22:37,253,609...37,305,769
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FANCD2
FA complementation group D2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12893777)
TreeGrafter MGI
PMID:12893777
GO_REF:0000118
NCBI chr 3:9,932,292...10,037,332
Ensembl chr 3:10,312,476...10,389,190
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HORMAD1
HORMA domain containing 1
acts_upstream_of_or_within
ISO
(PMID:22530760)
MGI
PMID:22530760
NCBI chr 1:126,054,585...126,077,361
Ensembl chr 1:129,704,451...129,726,691
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IHO1
interactor of HORMAD1 1
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr 3:49,122,120...49,181,228
Ensembl chr 3:50,239,250...50,259,890
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KASH5
KASH domain containing 5
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24062341)
Ensembl MGI TreeGrafter
PMID:24062341
GO_REF:0000107 GO_REF:0000118
NCBI chr19:46,402,586...46,432,002
Ensembl chr19:55,325,640...55,353,721
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LOC100972985
meiosis specific with OB-fold
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr16:835,420...874,178
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MAEL
maelstrom spermatogenic transposon silencer
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18694567)
Ensembl MGI
PMID:18694567
GO_REF:0000107
NCBI chr 1:142,341,646...142,442,521
Ensembl chr 1:146,195,482...146,228,669
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MAJIN
membrane anchored junction protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:30718482)
Ensembl MGI TreeGrafter
PMID:30718482
GO_REF:0000107 GO_REF:0000118
NCBI chr11:60,294,618...60,328,902
Ensembl chr11:63,635,508...63,669,168
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MEI4
meiotic double-stranded break formation protein 4
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:20551173)
Ensembl MGI TreeGrafter
PMID:20551173
GO_REF:0000107 GO_REF:0000118
NCBI chr 6:75,500,343...75,769,319
Ensembl chr 6:78,783,853...79,047,119
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MLH1
mutL homolog 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:8674118)
Ensembl MGI
PMID:8674118
GO_REF:0000107
NCBI chr 3:36,899,828...36,957,076
Ensembl chr 3:37,189,439...37,245,801
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MND1
meiotic nuclear divisions 1
involved_in
IEA
Ensembl
GO_REF:0000107
Ensembl chr 4:157,510,445...157,580,034
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MRE11
MRE11 homolog, double strand break repair nuclease
acts_upstream_of_or_within
ISO
(PMID:17291760)
MGI
PMID:17291760
NCBI chr11:89,418,537...89,500,705
Ensembl chr11:92,918,549...92,985,966
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MSH4
mutS homolog 4
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:10809667), (PMID:15467367)
Ensembl MGI
PMID:10809667 PMID:15467367
GO_REF:0000107
NCBI chr 1:75,011,947...75,130,036
Ensembl chr 1:76,983,852...77,099,896
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MSH5
mutS homolog 5
acts_upstream_of_or_within
ISO
(PMID:10809667), (PMID:15467367)
MGI
PMID:10809667 PMID:15467367
NCBI chr 6:31,401,343...31,424,665
Ensembl chr 6:32,290,511...32,311,085
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NDC1
NDC1 transmembrane nucleoporin
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24045954)
Ensembl MGI
PMID:24045954
GO_REF:0000107
NCBI chr 1:53,041,298...53,113,181
Ensembl chr 1:54,637,637...54,708,078
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PRDM9
PR/SET domain 9
involved_in
ISO
(MGI:6102131|PMID:25894966), (MGI:6114980|PMID:29478809)
UniProt
PMID:25894966 PMID:29478809
MGI:6102131 MGI:6114980
NCBI chr 5:86,847,131...86,856,802
Ensembl chr 5:92,377,523...92,395,486
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PSMC3IP
PSMC3 interacting protein
involved_in
IEA
Ensembl TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr17:14,738,205...14,744,215
Ensembl chr17:14,961,602...14,967,639
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RAD21L1
RAD21 cohesin complex component like 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:21743440)
Ensembl MGI
PMID:21743440
GO_REF:0000107
NCBI chr20:1,385,935...1,413,301
Ensembl chr20:1,153,384...1,231,383
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REC8
REC8 meiotic recombination protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17696610)
Ensembl MGI
PMID:17696610
GO_REF:0000107
NCBI chr14:4,948,100...4,956,492
Ensembl chr14:23,071,724...23,079,948
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RNF212
ring finger protein 212
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 4:1,167,176...1,259,080
Ensembl chr 4:1,102,342...1,146,153
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RNF212B
ring finger protein 212B
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr14:4,056,671...4,093,210
Ensembl chr14:22,153,247...22,188,319
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SIRT7
sirtuin 7
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:76,317,560...76,323,761
Ensembl chr17:82,020,077...82,026,289
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SPATA22
spermatogenesis associated 22
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22011390)
InterPro MGI Ensembl
PMID:22011390
GO_REF:0000002 GO_REF:0000107
NCBI chr17:3,120,296...3,532,343
Ensembl chr17:3,489,143...3,560,654
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SPO11
SPO11 initiator of meiotic double strand breaks
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18694567) (PMID:24589552)
Ensembl MGI
PMID:18694567 PMID:24589552
GO_REF:0000107
NCBI chr20:53,669,128...53,684,328
Ensembl chr20:54,948,661...54,963,384
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STAG3
STAG3 cohesin complex component
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24797475)
Ensembl MGI
PMID:24797475
GO_REF:0000107
NCBI chr 7:92,215,064...92,249,202
Ensembl chr 7:105,648,425...105,681,850
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SUN1
Sad1 and UNC84 domain containing 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24589552)
Ensembl MGI
PMID:24589552
GO_REF:0000107
NCBI chr 7:971,632...1,031,152
Ensembl chr 7:1,190,462...1,247,390
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SYCP1
synaptonemal complex protein 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 1:87,565,888...87,701,530
Ensembl chr 1:122,614,520...122,754,137
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SYCP3
synaptonemal complex protein 3
acts_upstream_of_or_within
ISO
(PMID:15870106)
MGI
PMID:15870106
NCBI chr12:99,311,260...99,322,007
Ensembl chr12:102,711,837...102,720,728
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TERB1
telomere repeat binding bouquet formation protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:30718482)
Ensembl MGI TreeGrafter
PMID:30718482
GO_REF:0000107 GO_REF:0000118
NCBI chr16:47,071,709...47,118,205
Ensembl chr16:66,175,538...66,220,511
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TERB2
telomere repeat binding bouquet formation protein 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:30718482)
TreeGrafter MGI
PMID:30718482
GO_REF:0000118
NCBI chr15:23,904,880...23,927,325
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TEX15
testis expressed 15, meiosis and synapsis associated
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18283110)
InterPro MGI
PMID:18283110
GO_REF:0000002
NCBI chr 8:30,145,628...30,232,903
Ensembl chr 8:27,334,129...27,420,049
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ZCWPW1
zinc finger CW-type and PWWP domain containing 1
involved_in acts_upstream_of_or_within
ISO
(MGI:6443266|PMID:32352380), (MGI:6467709|PMID:32744506) (MGI:6358520|PMID:31453335), (MGI:6442007|PMID:32374261)
UniProt ARUK-UCL
PMID:31453335 PMID:32352380 PMID:32374261 PMID:32744506
MGI:6358520 MGI:6442007 MGI:6443266 MGI:6467709
NCBI chr 7:92,429,776...92,457,943
Ensembl chr 7:105,832,031...105,859,995
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BRIP1
BRCA1 interacting helicase 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:26490168)
Ensembl MGI
PMID:26490168
GO_REF:0000107
NCBI chr17:55,786,568...55,973,366
Ensembl chr17:60,901,073...61,083,462
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CCNB1IP1
cyclin B1 interacting protein 1
involved_in acts_upstream_of_or_within
ISO
(MGI:5545848|PMID:24390283) (PMID:17784788)
UniProt MGI
PMID:17784788 PMID:24390283
MGI:5545848
NCBI chr14:1,182,025...1,205,471
Ensembl chr14:19,235,987...19,258,663
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MSH5
mutS homolog 5
involved_in
IEA
TreeGrafter
GO_REF:0000118
NCBI chr 6:31,401,343...31,424,665
Ensembl chr 6:32,290,511...32,311,085
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RNF212
ring finger protein 212
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 4:1,167,176...1,259,080
Ensembl chr 4:1,102,342...1,146,153
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SYCP1
synaptonemal complex protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22164254)
Ensembl MGI TreeGrafter
PMID:22164254
GO_REF:0000107 GO_REF:0000118
NCBI chr 1:87,565,888...87,701,530
Ensembl chr 1:122,614,520...122,754,137
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SYCP3
synaptonemal complex protein 3
involved_in acts_upstream_of_or_within
ISO
(MGI:2179610|PMID:12004129) (PMID:22164254)
UniProt MGI
PMID:12004129 PMID:22164254
MGI:2179610
NCBI chr12:99,311,260...99,322,007
Ensembl chr12:102,711,837...102,720,728
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TEX11
testis expressed 11
acts_upstream_of_or_within
ISO
(PMID:18316482)
MGI
PMID:18316482
NCBI chr X:59,796,821...60,175,517
Ensembl chr X:69,877,751...70,233,320
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UBE2A
ubiquitin conjugating enzyme E2 A
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr X:108,606,271...108,617,000
Ensembl chr X:119,034,235...119,049,655
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UBE2B
ubiquitin conjugating enzyme E2 B
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:12556476)
Ensembl MGI
PMID:12556476
GO_REF:0000107
NCBI chr 5:129,775,011...129,794,853
Ensembl chr 5:135,925,217...135,944,609
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SYCP1
synaptonemal complex protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22164254)
Ensembl TreeGrafter MGI
PMID:22164254
GO_REF:0000107 GO_REF:0000118
NCBI chr 1:87,565,888...87,701,530
Ensembl chr 1:122,614,520...122,754,137
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SYCP3
synaptonemal complex protein 3
acts_upstream_of_or_within
ISO
(PMID:22164254)
MGI
PMID:22164254
NCBI chr12:99,311,260...99,322,007
Ensembl chr12:102,711,837...102,720,728
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BAG6
BAG cochaperone 6
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 6:31,300,126...31,313,829
Ensembl chr 6:32,190,037...32,204,321
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C15H14orf39
chromosome 15 C14orf39 homolog
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr14:41,040,315...41,090,267
Ensembl chr14:59,304,040...59,351,956
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C1H1orf146
chromosome 1 C1orf146 homolog
involved_in
IEA
InterPro TreeGrafter Ensembl
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr 1:94,876,468...94,907,783
Ensembl chr 1:93,618,905...93,646,763
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CPEB1
cytoplasmic polyadenylation element binding protein 1
acts_upstream_of_or_within
ISO
(PMID:12815066) (PMID:11702780)
MGI
PMID:11702780 PMID:12815066
NCBI chr15:62,949,264...63,053,994
Ensembl chr15:80,443,096...80,526,948
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EHMT2
euchromatic histone lysine methyltransferase 2
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:17599069)
Ensembl MGI
PMID:17599069
GO_REF:0000107
NCBI chr 6:31,542,946...31,560,894
Ensembl chr 6:32,429,271...32,451,844
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HORMAD1
HORMA domain containing 1
involved_in
ISO
(MGI:5009722|PMID:21478856)
UniProt
PMID:21478856
MGI:5009722
NCBI chr 1:126,054,585...126,077,361
Ensembl chr 1:129,704,451...129,726,691
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LOC100977537
argonaute RISC component 4
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22863743)
Ensembl MGI
PMID:22863743
GO_REF:0000107
NCBI chr 1:35,072,045...35,122,418
Ensembl chr 1:36,249,038...36,299,259
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LOC129394329
pachytene checkpoint protein 2 homolog
involved_in
ISO
(MGI:4821667|PMID:20711356)
UniProt
PMID:20711356
MGI:4821667
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MCMDC2
minichromosome maintenance domain containing 2
acts_upstream_of_or_within
ISO
(PMID:27760146)
MGI
PMID:27760146
NCBI chr 8:63,412,462...63,465,258
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MEIOC
meiosis specific with coiled-coil domain
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr17:12,725,114...12,744,974
Ensembl chr17:12,901,882...12,920,285
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MLH3
mutL homolog 3
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:16260499)
Ensembl MGI
PMID:16260499
GO_REF:0000107
NCBI chr14:55,568,033...55,603,672
Ensembl chr14:74,413,319...74,445,749
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RAD21L1
RAD21 cohesin complex component like 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:24589552) (PMID:22711701)
Ensembl MGI
PMID:22711701 PMID:24589552
GO_REF:0000107
NCBI chr20:1,385,935...1,413,301
Ensembl chr20:1,153,384...1,231,383
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REC8
REC8 meiotic recombination protein
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22711701) (PMID:24589552)
Ensembl MGI
PMID:22711701 PMID:24589552
GO_REF:0000107
NCBI chr14:4,948,100...4,956,492
Ensembl chr14:23,071,724...23,079,948
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SHOC1
shortage in chiasmata 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr 9:82,816,269...82,916,515
Ensembl chr 9:110,978,485...111,085,856
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SPO11
SPO11 initiator of meiotic double strand breaks
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:27760146) (PMID:24589552)
Ensembl MGI
PMID:24589552 PMID:27760146
GO_REF:0000107
NCBI chr20:53,669,128...53,684,328
Ensembl chr20:54,948,661...54,963,384
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SYCE1
synaptonemal complex central element protein 1
involved_in
IEA
InterPro
GO_REF:0000002
Ensembl chr10:134,866,705...134,878,566
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SYCE1L
synaptonemal complex central element protein 1 like
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr16:57,774,445...57,789,221
Ensembl chr16:77,120,694...77,135,476
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SYCE2
synaptonemal complex central element protein 2
involved_in
IEA
InterPro
GO_REF:0000002
NCBI chr19:12,459,646...12,481,833
Ensembl chr19:13,203,595...13,224,052
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SYCE3
synaptonemal complex central element protein 3
involved_in
IEA
Ensembl TreeGrafter InterPro
GO_REF:0000002 GO_REF:0000107 GO_REF:0000118
NCBI chr22:30,797,389...30,809,517
Ensembl chr22:49,908,095...49,913,903
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SYCP1
synaptonemal complex protein 1
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22164254)
InterPro MGI Ensembl
PMID:22164254
GO_REF:0000002 GO_REF:0000107
NCBI chr 1:87,565,888...87,701,530
Ensembl chr 1:122,614,520...122,754,137
G
SYCP3
synaptonemal complex protein 3
involved_in acts_upstream_of_or_within
ISO
(MGI:1352918|PMID:10678170) (PMID:22164254)
UniProt MGI
PMID:10678170 PMID:22164254
MGI:1352918
NCBI chr12:99,311,260...99,322,007
Ensembl chr12:102,711,837...102,720,728
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SYDE1
synapse defective Rho GTPase homolog 1
acts_upstream_of_or_within
ISO
(PMID:23791195)
MGI
PMID:23791195
NCBI chr19:14,640,493...14,648,080
Ensembl chr19:15,625,096...15,631,600
G
TERB2
telomere repeat binding bouquet formation protein 2
acts_upstream_of_or_within
ISO
(PMID:30718482)
MGI
PMID:30718482
NCBI chr15:23,904,880...23,927,325
G
TEX11
testis expressed 11
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18316482)
TreeGrafter MGI
PMID:18316482
GO_REF:0000118
NCBI chr X:59,796,821...60,175,517
Ensembl chr X:69,877,751...70,233,320
G
TEX12
testis expressed 12
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:22164254)
TreeGrafter MGI
PMID:22164254
GO_REF:0000118
NCBI chr11:107,048,417...107,053,655
Ensembl chr11:110,817,016...110,896,829
G
TEX15
testis expressed 15, meiosis and synapsis associated
involved_in acts_upstream_of_or_within
IEA ISO
(PMID:18283110)
TreeGrafter MGI
PMID:18283110
GO_REF:0000118
NCBI chr 8:30,145,628...30,232,903
Ensembl chr 8:27,334,129...27,420,049
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all