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ONTOLOGY REPORT - ANNOTATIONS

Term:protein targeting to lysosome
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Accession:GO:0006622 term browser browse the term
Definition:The process of directing proteins towards the lysosome using signals contained within the protein.
Synonyms:exact_synonym: protein-lysosome targeting


show annotations for term's descendants           Sort by:
protein targeting to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap3b1 adaptor related protein complex 3 subunit beta 1 acts_upstream_of_or_within ISO MGI:1856989 (PMID:14557411) RGD PMID:14557411 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Ap4m1 adaptor related protein complex 4 subunit mu 1 involved_in ISO (PMID:11139587) RGD PMID:11139587 NCBI chr12:17,049,766...17,055,954
Ensembl chr12:17,049,777...17,058,026 		JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 involved_in ISO
ISS		 (PMID:16885419)
GO_REF:0000024		 RGD
UniProt		 PMID:16885419 GO_REF:0000024 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613 		JBrowse link
G Gga3 golgi associated, gamma adaptin ear containing, ARF binding protein 3 involved_in ISO UniProtKB:P46934 (PMID:17116753) RGD PMID:17116753 NCBI chr10:100,825,427...100,843,422
Ensembl chr10:100,825,426...100,844,462 		JBrowse link
G Hgs hepatocyte growth factor-regulated tyrosine kinase substrate involved_in ISO
IEA		 (PMID:18767904)
GO_REF:0000107		 RGD
Ensembl		 PMID:18767904 GO_REF:0000107 NCBI chr10:105,739,617...105,757,838
Ensembl chr10:105,739,296...105,757,835 		JBrowse link
G Laptm5 lysosomal protein transmembrane 5 involved_in ISO (MGI:3803048|PMID:18619870) RGD PMID:18619870 MGI:3803048 NCBI chr 5:143,087,759...143,109,807
Ensembl chr 5:143,087,759...143,109,807 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor IMP chorionic gonadotropin after receptor internalization RGD PMID:10847593 RGD:2292601 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G M6pr mannose-6-phosphate receptor, cation dependent involved_in IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 4:155,501,080...155,510,219
Ensembl chr 4:155,500,921...155,510,216 		JBrowse link
G M6pr-ps1 mannose-6-phosphate receptor, cation dependent, pseudogene 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:82,129,168...82,131,403
Ensembl chr  X:82,129,322...82,130,158 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 acts_upstream_of_or_within ISO (PMID:25327288) RGD PMID:25327288 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Ndp norrin cystine knot growth factor NDP acts_upstream_of_or_within ISO (PMID:28675177) RGD PMID:28675177 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IEA		 UniProtKB:Q9NZ52 (PMID:17116753)
GO_REF:0000107		 RGD
Ensembl		 PMID:17116753 GO_REF:0000107 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Pxk PX domain containing serine/threonine kinase involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:16,759,857...16,828,452
Ensembl chr15:16,759,862...16,828,444 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family involved_in ISO (PMID:22115783) RGD PMID:22115783 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Scarb2 scavenger receptor class B, member 2 involved_in ISO
IBA
IEA		 (PMID:18022370)
GO_REF:0000033
GO_REF:0000107
(MGI:3773765|PMID:18022370)		 RGD
GO_Central
Ensembl		 PMID:18022370 GO_REF:0000033 GO_REF:0000107 MGI:3773765 NCBI chr14:15,558,271...15,609,813
Ensembl chr14:15,558,236...15,609,813 		JBrowse link
G Snx16 sorting nexin 16 involved_in ISO
IBA
IEA
ISS		 (PMID:12813048)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000024		 RGD
GO_Central
Ensembl
UniProt		 PMID:12813048 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:91,335,896...91,357,622
Ensembl chr 2:91,336,092...91,357,619 		JBrowse link
G Sorl1 sortilin related receptor 1 involved_in ISO
IBA		 (PMID:24523320)
GO_REF:0000033		 RGD
GO_Central		 PMID:24523320 GO_REF:0000033 NCBI chr 8:42,341,704...42,504,435
Ensembl chr 8:42,341,704...42,504,513 		JBrowse link
G Sort1 sortilin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:4397584 (PMID:19732768)		 Ensembl
RGD		 PMID:19732768 GO_REF:0000107 NCBI chr 2:195,924,033...196,002,354
Ensembl chr 2:195,924,099...196,002,354 		JBrowse link
G Vps4a vacuolar protein sorting 4 homolog A involved_in ISO
IEA		 (PMID:16973552)
GO_REF:0000107		 RGD
Ensembl		 PMID:16973552 GO_REF:0000107 NCBI chr19:34,934,999...34,948,888
Ensembl chr19:34,934,961...34,948,887 		JBrowse link
G Vps53 VPS53 subunit of GARP complex involved_in ISO (PMID:28658628) RGD PMID:28658628 NCBI chr10:60,919,820...61,038,674
Ensembl chr10:60,919,820...61,038,676 		JBrowse link
G Vps54 VPS54 subunit of GARP complex involved_in IEA
ISO		 GO_REF:0000107
MGI:1857091 (PMID:28658628), (PMID:32345721)		 Ensembl
RGD		 PMID:28658628 PMID:32345721 GO_REF:0000107 NCBI chr14:95,378,821...95,455,871
Ensembl chr14:95,378,012...95,455,857 		JBrowse link
G Washc1 WASH complex subunit 1 involved_in ISO (PMID:20175130) RGD PMID:20175130 NCBI chr 9:105,722,779...105,830,836
Ensembl chr 9:105,722,899...105,733,009 		JBrowse link
G Zfyve16 zinc finger FYVE-type containing 16 involved_in ISO
IBA		 (PMID:11546807)
GO_REF:0000033		 RGD
GO_Central		 PMID:11546807 GO_REF:0000033 NCBI chr 2:23,713,018...23,757,576
Ensembl chr 2:23,713,766...23,756,990 		JBrowse link
N-glycan processing to lysosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gnptab N-acetylglucosamine-1-phosphate transferase subunits alpha and beta involved_in ISO
IBA		 (PMID:19938078), (PMID:25505245)
GO_REF:0000033		 RGD
GO_Central		 PMID:19938078 PMID:25505245 GO_REF:0000033 NCBI chr 7:22,800,502...22,866,336
Ensembl chr 7:22,800,485...22,866,933 		JBrowse link
protein targeting to lysosome involved in chaperone-mediated autophagy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Clu clusterin involved_in ISO
IEA		 (PMID:9228033)
GO_REF:0000107		 RGD
Ensembl		 PMID:9228033 GO_REF:0000107 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Haus8l2 HAUS augmin-like complex, subunit 8 like 2 involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr11:5,628,432...5,630,535
Ensembl chr11:5,628,427...5,630,533 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:11559757), (PMID:26212789), (PMID:36586411)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:11559757 PMID:26212789 PMID:36586411 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 involved_in
acts_upstream_of_or_within		 ISO
ISS
IMP
IGI
IEA
IBA		 (PMID:27628032)
GO_REF:0000024
(MGI:5805578|PMID:27628032)
PMID:18644871
GO_REF:0000107
GO_REF:0000033		 RGD
UniProt
Ensembl
GO_Central		 PMID:27628032 PMID:18644871 PMID:18644871 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:5805578, RGD:10412301, RGD:10412301 NCBI chr  X:117,173,097...117,222,090
Ensembl chr  X:117,057,606...117,260,522 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    localization 5613
      cellular localization 3656
        intracellular transport 1397
          intracellular protein transport 691
            protein targeting to vacuole 45
              protein targeting to lysosome 28
                N-glycan processing to lysosome 1
                protein targeting to lysosome involved in chaperone-mediated autophagy 4
Path 2
Term Annotations click to browse term
  biological_process 19692
    localization 5613
      macromolecule localization 3167
        cellular macromolecule localization 2682
          protein localization 2670
            protein localization to organelle 1043
              establishment of protein localization to organelle 486
                establishment of protein localization to vacuole 58
                  protein targeting to vacuole 45
                    protein targeting to lysosome 28
                      N-glycan processing to lysosome 1
                      protein targeting to lysosome involved in chaperone-mediated autophagy 4
paths to the root