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ONTOLOGY REPORT - ANNOTATIONS

Term:voltage-gated calcium channel activity
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Accession:GO:0005245 term browser browse the term
Definition:Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
Synonyms:exact_synonym: depolarization-activated voltage gated calcium channel activity;   depolarization-activated voltage-gated calcium channel;   voltage-dependent calcium channel activity;   voltage-gated calcium ion channel activity;   voltage-sensitive calcium channel
 narrow_synonym: dihydropyridine-sensitive calcium channel activity
 broad_synonym: depolarization-activated calcium channel
 alt_id: GO:0010173;   GO:0015270
 xref: Reactome:R-HSA-5577213 "LTCC multimer transports Ca2+ from extracellular region to cytosol";   Reactome:R-HSA-9701055 "TRPA1 tetramer transports Ca2+ from extracellular region to cytosol";   Reactome:R-HSA-9701141 "TRPV1 transports Ca2+ from extracellular region to cytosol";   reactome:R-HSA-265645 "Calcium Influx through Voltage-gated Calcium Channels"

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voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACHD1 cache domain containing 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr20:68,389,853...68,615,603
Ensembl chr20:68,387,320...68,614,512 		JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO (PMID:21883149)
(PMID:9614225)
(PMID:8632762)
(PMID:10611370)
(PMID:9857013)
(PMID:12827191)
(PMID:12151514)
(PMID:10753886), (PMID:12451115)
PMID:15980432		 ARUK-UCL
MGI
UniProt
RGD		 PMID:8632762 PMID:9593738 PMID:9614225 PMID:9857013 PMID:10611370 More... RGD:1582495 RGD:634678 RGD:8553366 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables IEA InterPro GO_REF:0000002 Ensembl chr 6:11,933,557...12,181,901 JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO
IEA		 RGD
InterPro		 PMID:10864934 GO_REF:0000002 RGD:1299351 NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16483597 PMID:16554304 GO_REF:0000002 GO_REF:0000107 RGD:1580158 RGD:1582591 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables ISO
IEA		 RGD
UniProt
InterPro
Ensembl		 PMID:11487617 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 RGD:727563 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables ISO
IEA		 RGD
InterPro
Ensembl		 PMID:21611731 GO_REF:0000002 GO_REF:0000107 RGD:7205480 NCBI chr25:47,589,859...47,924,081
Ensembl chr25:47,597,808...47,922,969 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables ISO (PMID:15897456), (PMID:27226626)
(PMID:16155113)		 UniProt
MGI		 PMID:15897456 PMID:16155113 PMID:27226626 NCBI chr  X:46,304,831...46,330,562 JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables IEA Ensembl
InterPro		 GO_REF:0000002 GO_REF:0000107 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H enables IEA InterPro GO_REF:0000002 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I enables IEA InterPro GO_REF:0000002 NCBI chr19:22,129,795...22,264,485
Ensembl chr19:22,143,980...22,261,098 		JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables IEA InterPro
Ensembl
UniProt		 GO_REF:0000002 GO_REF:0000107 GO_REF:0000117 NCBI chr25:28,288,483...28,363,231
Ensembl chr25:28,289,342...28,363,327 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 enables
contributes_to		 ISO
IEA		 (PMID:11160515), (PMID:17224476) RGD
TreeGrafter
Ensembl
UniProtKB		 PMID:11160515 PMID:11604404 PMID:17224476 GO_REF:0000107 GO_REF:0000118 RGD:625474 NCBI chr21:66,449,154...66,937,643
Ensembl chr21:66,770,578...66,934,898 		JBrowse link
G CACNA2D2 calcium voltage-gated channel auxiliary subunit alpha2delta 2 enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:12606261 GO_REF:0000107 GO_REF:0000118 RGD:632381 NCBI chr22:11,751,026...11,891,407
Ensembl chr22:11,749,727...11,890,924 		JBrowse link
G CACNA2D3 calcium voltage-gated channel auxiliary subunit alpha2delta 3 enables ISO
IEA		 RGD
TreeGrafter		 PMID:12606261 GO_REF:0000118 RGD:632381 NCBI chr22:15,506,289...16,433,892
Ensembl chr22:15,700,522...16,433,899 		JBrowse link
G CACNA2D4 calcium voltage-gated channel auxiliary subunit alpha2delta 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr11:1,837,811...1,972,523
Ensembl chr11:1,841,070...1,971,874 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 contributes_to
enables		 ISO
IEA		 RGD
InterPro
Ensembl		 PMID:16049183 PMID:16554304 GO_REF:0000002 GO_REF:0000107 RGD:1582495 RGD:1582591 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 RGD
Ensembl
InterPro		 PMID:16049183 GO_REF:0000002 GO_REF:0000107 RGD:1582495 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 contributes_to
enables		 ISO
IEA		 (PMID:11160515) UniProtKB
Ensembl
InterPro
RGD		 PMID:11160515 PMID:14559910 GO_REF:0000002 GO_REF:0000107 RGD:1358466 NCBI chr11:45,056,116...45,071,076
Ensembl chr11:45,061,046...45,071,544 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 enables
contributes_to		 ISO
IEA		 (PMID:16525042) RGD
InterPro
UniProtKB		 PMID:12821675 PMID:16525042 GO_REF:0000002 RGD:737839 NCBI chr10:37,240,749...37,518,174
Ensembl chr10:37,246,991...37,388,059 		JBrowse link
G CACNG1 calcium voltage-gated channel auxiliary subunit gamma 1 enables IEA InterPro
Ensembl		 GO_REF:0000002 GO_REF:0000107 NCBI chr16:54,383,328...54,397,331
Ensembl chr16:54,383,204...54,396,610 		JBrowse link
G CACNG2 calcium voltage-gated channel auxiliary subunit gamma 2 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr19:19,263,950...19,406,952
Ensembl chr19:19,267,426...19,406,883 		JBrowse link
G CACNG3 calcium voltage-gated channel auxiliary subunit gamma 3 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 5:21,975,706...22,081,428
Ensembl chr 5:21,976,428...22,081,547 		JBrowse link
G CACNG4 calcium voltage-gated channel auxiliary subunit gamma 4 enables IEA InterPro
TreeGrafter		 GO_REF:0000002 GO_REF:0000118 NCBI chr16:54,413,981...54,482,707
Ensembl chr16:54,413,965...54,482,561 		JBrowse link
G CACNG5 calcium voltage-gated channel auxiliary subunit gamma 5 enables IEA TreeGrafter GO_REF:0000118 NCBI chr16:54,561,040...54,612,026
Ensembl chr16:54,561,317...54,569,097 		JBrowse link
G CACNG7 calcium voltage-gated channel auxiliary subunit gamma 7 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:46,602,072...46,631,975
Ensembl chr 6:46,605,245...46,632,416 		JBrowse link
G CACNG8 calcium voltage-gated channel auxiliary subunit gamma 8 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 6:46,649,793...46,670,918
Ensembl chr 6:46,649,865...46,670,452 		JBrowse link
G CALHM1 calcium homeostasis modulator 1 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:96,500,716...96,507,439
Ensembl chr 9:96,502,577...96,506,072 		JBrowse link
G CATSPER1 cation channel sperm associated 1 enables IEA TreeGrafter GO_REF:0000118 NCBI chr 1:8,231,436...8,241,189
Ensembl chr 1:8,231,915...8,241,048 		JBrowse link
G CATSPER2 cation channel sperm associated 2 enables ISO (PMID:21412338) UniProt PMID:21412338 NCBI chr26:39,300,273...39,325,846 JBrowse link
G CATSPER3 cation channel sperm associated 3 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr23:37,740,072...37,791,261
Ensembl chr23:37,743,673...37,791,176 		JBrowse link
G CATSPER4 cation channel sperm associated 4 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:106,564,858...106,577,383
Ensembl chr20:106,565,284...106,576,779 		JBrowse link
G GRM7 glutamate metabotropic receptor 7 enables ISO (MGI:3690146|PMID:12065412) UniProt PMID:12065412 MGI:3690146 NCBI chr22:42,901,451...43,779,815 JBrowse link
G ITGAV integrin subunit alpha V enables ISO (PMID:18395422) UniProt PMID:18395422 NCBI chr10:72,125,710...72,216,757
Ensembl chr10:72,125,962...72,216,809 		JBrowse link
G NCS1 neuronal calcium sensor 1 enables ISO PMID:17502602 UniProt PMID:17502602 RGD:8553610 NCBI chr12:7,910,495...7,975,650 JBrowse link
G OPRM1 opioid receptor mu 1 enables ISO PMID:1846076 UniProt PMID:1846076 RGD:8656003 NCBI chr13:81,568,295...81,650,005
Ensembl chr13:81,568,732...81,625,088 		JBrowse link
G PKD2 polycystin 2, transient receptor potential cation channel enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 7:36,369,226...36,445,713
Ensembl chr 7:36,369,524...36,443,612 		JBrowse link
G RYR1 ryanodine receptor 1 enables ISO (MGI:3764002|PMID:18003898), (PMID:12954602) UniProt PMID:12954602 PMID:18003898 MGI:3764002 NCBI chr 6:33,080,443...33,234,478
Ensembl chr 6:33,080,758...33,213,788 		JBrowse link
G TMC1 transmembrane channel like 1 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr12:83,672,786...83,883,985
Ensembl chr12:83,735,988...83,877,251 		JBrowse link
G TMC2 transmembrane channel like 2 enables IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:53,903,305...54,002,599
Ensembl chr 2:53,903,842...53,979,535 		JBrowse link
G TPCN2 two pore segment channel 2 NOT|enables ISO (PMID:23063126)
(MGI:5285159|PMID:20495006)		 UniProt PMID:20495006 PMID:23063126 MGI:5285159 NCBI chr 1:5,491,476...5,529,015
Ensembl chr 1:5,490,910...5,528,718 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:14712238 RGD:1303969 NCBI chr 8:67,698,067...67,754,407
Ensembl chr 8:67,698,786...67,751,885 		JBrowse link
high voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO (PMID:23376566)
(PMID:11756409)
(PMID:11344116)
(PMID:12040045)
(PMID:10908603)
(PMID:11718712), (PMID:9742139)
(PMID:12065603), (PMID:12401561), (PMID:12624181), (PMID:15548652)
(PMID:21883149), (PMID:24836863), (PMID:26716990)		 ARUK-UCL
MGI
RGD
UniProt		 PMID:9742139 PMID:10908603 PMID:11344116 PMID:11718712 PMID:11756409 More... RGD:7205477 RGD:7205480 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables IEA TreeGrafter GO_REF:0000118 Ensembl chr 6:11,933,557...12,181,901 JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:18701069 GO_REF:0000107 GO_REF:0000118 RGD:7205441 NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:17068255 GO_REF:0000107 GO_REF:0000118 RGD:7205477 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
TreeGrafter
Ensembl
RGD		 PMID:1309651 PMID:18322004 GO_REF:0000107 GO_REF:0000118 RGD:7207845 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables IEA TreeGrafter GO_REF:0000118 NCBI chr25:47,589,859...47,924,081
Ensembl chr25:47,597,808...47,922,969 		JBrowse link
G CACNA1F calcium voltage-gated channel subunit alpha1 F enables ISO (PMID:27226626) UniProt PMID:27226626 NCBI chr  X:46,304,831...46,330,562 JBrowse link
G CACNA1S calcium voltage-gated channel subunit alpha1 S enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:7479909 GO_REF:0000107 GO_REF:0000118 RGD:634679 NCBI chr25:28,288,483...28,363,231
Ensembl chr25:28,289,342...28,363,327 		JBrowse link
G CACNB1 calcium voltage-gated channel auxiliary subunit beta 1 enables ISO (PMID:11756409) MGI PMID:11756409 NCBI chr16:66,971,379...66,994,031
Ensembl chr16:66,971,459...66,996,095 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:1309651) BHF-UCL
Ensembl		 PMID:1309651 GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617 		JBrowse link
G CACNB3 calcium voltage-gated channel auxiliary subunit beta 3 contributes_to ISO PMID:25527503 BHF-UCL PMID:25527503 RGD:11059598 NCBI chr11:45,056,116...45,071,076
Ensembl chr11:45,061,046...45,071,544 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 contributes_to ISO (PMID:11880487) UniProtKB PMID:11880487 NCBI chr10:37,240,749...37,518,174
Ensembl chr10:37,246,991...37,388,059 		JBrowse link
low voltage-gated calcium channel activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:16935432 PMID:18759855 PMID:18760992 GO_REF:0000107 GO_REF:0000118 RGD:2308879 RGD:7175320 RGD:7207257 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNA1H calcium voltage-gated channel subunit alpha1 H enables ISO
IEA		 RGD
TreeGrafter
Ensembl		 PMID:11073957 PMID:16935432 GO_REF:0000107 GO_REF:0000118 RGD:68748 RGD:7207257 NCBI chr 5:1,039,709...1,106,212
Ensembl chr 5:1,078,973...1,106,507 		JBrowse link
G CACNA1I calcium voltage-gated channel subunit alpha1 I enables ISO
IEA		 RGD
TreeGrafter		 PMID:16935432 PMID:18760992 GO_REF:0000118 RGD:7175320 RGD:7207257 NCBI chr19:22,129,795...22,264,485
Ensembl chr19:22,143,980...22,261,098 		JBrowse link
voltage-gated calcium channel activity involved in AV node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C enables IEA Ensembl GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:17224476) BHF-UCL
Ensembl		 PMID:17224476 GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617 		JBrowse link
voltage-gated calcium channel activity involved in bundle of His cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 contributes_to
enables		 ISO
IEA		 (PMID:21383000) BHF-UCL
Ensembl		 PMID:21383000 GO_REF:0000107 NCBI chr21:66,449,154...66,937,643
Ensembl chr21:66,770,578...66,934,898 		JBrowse link
voltage-gated calcium channel activity involved in cardiac muscle cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1C calcium voltage-gated channel subunit alpha1 C contributes_to
enables		 ISO
IEA		 (PMID:17224476) BHF-UCL
Ensembl		 PMID:17224476 GO_REF:0000107 NCBI chr11:2,107,722...2,753,970
Ensembl chr11:2,508,705...2,752,991 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 contributes_to
enables		 ISO
IEA		 (PMID:17224476) BHF-UCL
Ensembl		 PMID:17224476 GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617 		JBrowse link
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1A calcium voltage-gated channel subunit alpha1 A enables ISO (PMID:25741235) SynGO PMID:25741235 NCBI chr 6:11,883,353...12,307,023 JBrowse link
G CACNA1B calcium voltage-gated channel subunit alpha1 B enables ISO PMID:7832825 SynGO PMID:7832825 RGD:13792530 NCBI chr12:75,441...335,980
Ensembl chr12:78,011...335,820 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables ISO (PMID:10929716) SynGO PMID:10929716 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E enables ISO PMID:19193890 SynGO PMID:19193890 RGD:13792544 NCBI chr25:47,589,859...47,924,081
Ensembl chr25:47,597,808...47,922,969 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 enables IEA Ensembl GO_REF:0000107 NCBI chr 9:18,075,436...18,470,985
Ensembl chr 9:18,332,165...18,469,617 		JBrowse link
G CACNB4 calcium voltage-gated channel auxiliary subunit beta 4 enables ISO (PMID:10322048) SynGO PMID:10322048 NCBI chr10:37,240,749...37,518,174
Ensembl chr10:37,246,991...37,388,059 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B enables ISO PMID:17067296 SynGO PMID:17067296 RGD:13702319 NCBI chr13:2,143,646...2,145,943
Ensembl chr13:2,144,313...2,145,485 		JBrowse link
G RIMBP2 RIMS binding protein 2 enables ISO (PMID:26402606) SynGO PMID:26402606 NCBI chr11:125,770,331...126,170,664 JBrowse link
G TSPOAP1 TSPO associated protein 1 enables ISO (PMID:26402606) SynGO PMID:26402606 NCBI chr16:35,071,519...35,099,174
Ensembl chr16:35,072,385...35,096,057 		JBrowse link
voltage-gated calcium channel activity involved SA node cell action potential term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CACNA1D calcium voltage-gated channel subunit alpha1 D enables IEA Ensembl GO_REF:0000107 NCBI chr22:14,868,459...15,195,002
Ensembl chr22:15,027,565...15,197,101 		JBrowse link
G CACNA1G calcium voltage-gated channel subunit alpha1 G enables ISO (MGI:3714901|PMID:16690884) BHF-UCL PMID:16690884 MGI:3714901 NCBI chr16:42,710,640...42,776,736
Ensembl chr16:42,708,638...42,768,843 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18050
    transporter activity 1200
      transmembrane transporter activity 1111
        monoatomic ion transmembrane transporter activity 743
          monoatomic ion channel activity 457
            monoatomic cation channel activity 350
              calcium channel activity 121
                voltage-gated calcium channel activity 45
                  high voltage-gated calcium channel activity 12
                  intermediate voltage-gated calcium channel activity 0
                  light-activated voltage-gated calcium channel activity 0
                  low voltage-gated calcium channel activity 3
                  voltage-gated calcium channel activity involved in cardiac muscle cell action potential + 5
                  voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels 0
                  voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels + 9
Path 2
Term Annotations click to browse term
  molecular_function 18050
    transporter activity 1200
      transmembrane transporter activity 1111
        passive transmembrane transporter activity 521
          channel activity 521
            gated channel activity 334
              voltage-gated channel activity 180
                voltage-gated monoatomic ion channel activity 177
                  voltage-gated monoatomic cation channel activity 150
                    voltage-gated calcium channel activity 45
                      high voltage-gated calcium channel activity 12
                      intermediate voltage-gated calcium channel activity 0
                      light-activated voltage-gated calcium channel activity 0
                      low voltage-gated calcium channel activity 3
                      voltage-gated calcium channel activity involved in cardiac muscle cell action potential + 5
                      voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels 0
                      voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels + 9
paths to the root