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ONTOLOGY REPORT - ANNOTATIONS


Term:glutamine synthetase activity
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Accession:GO:0004356 term browser browse the term
Definition:Catalysis of the reaction: ATP + L-glutamate + NH4+ = ADP + H+ + L-glutamine + phosphate.
Synonyms:exact_synonym: glutamate-ammonia ligase activity
 related_synonym: L-glutamine synthetase activity
 xref: EC:6.3.1.2;   KEGG_REACTION:R00253;   MetaCyc:GLUTAMINESYN-RXN;   RHEA:16169;   reactome:R-HSA-70606 "glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL]"



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glutamine synthetase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glul glutamate-ammonia ligase enables IDA
ISO
IBA
IEA
(PMID:30158707), (PMID:36289327)
GO_REF:0000033
GO_REF:0000107
GO_REF:0000002
RGD
GO_Central
Ensembl
InterPro
PMID:30158707 PMID:36289327 PMID:4403443 PMID:28323 GO_REF:0000002 GO_REF:0000033 GO_REF:0000107, RGD:2301548, RGD:2301547 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108
JBrowse link
G Lgsn lengsin, lens protein with glutamine synthetase domain enables
NOT|enables
IEA
IBA
GO_REF:0000002
GO_REF:0000033
InterPro
GO_Central
GO_REF:0000002 GO_REF:0000033 NCBI chr 9:33,416,362...33,447,919
Ensembl chr 9:33,420,484...33,447,907
JBrowse link

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  molecular_function 20483
    catalytic activity 6036
      ligase activity 177
        ligase activity, forming carbon-nitrogen bonds 51
          acid-ammonia (or amide) ligase activity 3
            ammonia ligase activity 2
              glutamine synthetase activity 2
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