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ONTOLOGY REPORT - ANNOTATIONS

Term:SAGA complex
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Accession:GO:0000124 term browser browse the term
Definition:A SAGA-type histone acetyltransferase complex that deubiquitinates H2A and/or H2B. This complex is organized into several functional submodules: a structural core including the activator binding module and consisting of ADA1 or a homolog, members of the SPT and TAF protein families as well as promotor recruitment factor TRRAP/TRA1, a histone acetyltransferase (HAT) module consisting of GCN5/KAT2A or PCAF/KAT2B, ADA2, ADA3/NGG1, and SGF29 or homologues thereof, a histone deubiquitinase (DUB) module consisting of ATXN7/SGF73, ATXN7L3/SGF11, ENY2/SUS1 and USP22/UBP8 or homologues thereof, and in some taxa a splicing module consisting of SF3B3 and SF3B5 or homologues thereof (not in fungi). In budding yeast also contains Spt8 which distinguishes it from SAGA-like (SLIK) complex (GO:0046695).
Synonyms:exact_synonym: Spt-Ada-Gcn5-acetyltransferase complex
 narrow_synonym: PCAF complex;   PCAF histone acetylase-associated complex;   SPT3-TAF9-PCAF acetylase complex
 related_synonym: SPT3-TAF9-GCN5 acetylase complex;   STAGA coactivator complex;   STAGA complex
 alt_id: GO:0000125;   GO:0030914


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SAGA complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07038858.1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 Ensembl chr  X:58,646,432...58,649,965 JBrowse link
G Atxn7l3 ataxin 7-like 3 part_of ISO
IBA		 (PMID:18206972), (PMID:27601583)
GO_REF:0000033		 RGD
GO_Central		 PMID:18206972 PMID:27601583 GO_REF:0000033 NCBI chr10:87,242,843...87,250,186
Ensembl chr10:87,243,587...87,250,620 		JBrowse link
G Eny2 ENY2, transcription and export complex 2 subunit part_of ISO
IBA		 (PMID:18206972), (PMID:23591820), (PMID:27601583)
GO_REF:0000033		 RGD
GO_Central		 PMID:18206972 PMID:23591820 PMID:27601583 GO_REF:0000033 NCBI chr 7:75,581,215...75,605,903
Ensembl chr 7:75,581,240...75,605,897 		JBrowse link
G Kat2a lysine acetyltransferase 2A part_of ISO (PMID:11564863)
(PMID:19103755)		 RGD PMID:11564863 PMID:19103755 NCBI chr10:85,632,216...85,640,561
Ensembl chr10:85,632,216...85,640,166 		JBrowse link
G Sgf29 SAGA complex associated factor 29 part_of IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 1:181,238,458...181,271,931
Ensembl chr 1:181,238,468...181,274,781 		JBrowse link
G Supt20h SPT20 homolog, SAGA complex component part_of IEA
IBA		 GO_REF:0000002
GO_REF:0000033		 InterPro
GO_Central		 GO_REF:0000002 GO_REF:0000033 NCBI chr 2:138,897,316...138,930,493
Ensembl chr 2:138,897,416...138,930,495 		JBrowse link
G Supt20hl1 Supt20h like 1 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:58,708,504...58,758,962
Ensembl chr  X:58,708,504...58,758,960 		JBrowse link
G Supt20hl2 SUPT20H like 2 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:58,645,548...58,653,436
Ensembl chr  X:58,646,432...58,649,965 		JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component part_of ISO (PMID:11564863)
(PMID:28893950)		 RGD PMID:11564863 PMID:28893950 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706 		JBrowse link
G Supt7l SPT7 like, STAGA complex subunit gamma part_of ISO (PMID:11564863) RGD PMID:11564863 NCBI chr 6:24,933,941...24,944,656
Ensembl chr 6:24,933,923...24,944,654 		JBrowse link
G Tada1 transcriptional adaptor 1 part_of ISO
IEA
IBA		 (PMID:11564863)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:11564863 GO_REF:0000033 GO_REF:0000107 NCBI chr13:78,632,908...78,646,863
Ensembl chr13:78,632,866...78,647,504 		JBrowse link
G Tada2a transcriptional adaptor 2A part_of ISO (PMID:9674425) RGD PMID:9674425 NCBI chr10:68,966,502...69,014,149
Ensembl chr10:68,966,502...69,014,105 		JBrowse link
G Tada2b transcriptional adaptor 2B part_of ISO (PMID:19103755) RGD PMID:19103755 NCBI chr14:74,279,286...74,290,758
Ensembl chr14:74,279,217...74,290,755 		JBrowse link
G Tada3 transcriptional adaptor 3 part_of ISO
IBA		 (PMID:11564863)
GO_REF:0000033
(PMID:19103755)		 RGD
GO_Central		 PMID:11564863 PMID:19103755 GO_REF:0000033 NCBI chr 4:146,510,213...146,521,975
Ensembl chr 4:146,510,246...146,521,590 		JBrowse link
G Taf10 TATA-box binding protein associated factor 10 part_of ISO
IBA		 (PMID:11564863), (PMID:9674425)
GO_REF:0000033		 RGD
GO_Central		 PMID:9674425 PMID:11564863 GO_REF:0000033 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376 		JBrowse link
G Taf12 TATA-box binding protein associated factor 12 part_of ISO (PMID:11564863)
(PMID:9674425)
(PMID:19103755)		 RGD PMID:9674425 PMID:11564863 PMID:19103755 NCBI chr 5:144,472,816...144,490,299
Ensembl chr 5:144,472,841...144,488,849 		JBrowse link
G Taf5l1 TATA-box binding protein associated factor 5 like 1 part_of ISO (PMID:11564863) RGD PMID:11564863 NCBI chr19:51,991,704...52,011,001
Ensembl chr19:51,991,708...52,011,295 		JBrowse link
G Taf6 TATA-box binding protein associated factor 6 part_of IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr12:17,055,864...17,064,244
Ensembl chr12:17,055,873...17,064,247 		JBrowse link
G Taf6l TATA-box binding protein associated factor 6 like part_of ISO (PMID:11564863) RGD PMID:11564863 NCBI chr 1:205,672,147...205,684,721
Ensembl chr 1:205,672,149...205,684,655 		JBrowse link
G Taf9 TATA-box binding protein associated factor 9 part_of ISO
IEA
IBA		 (PMID:11564863), (PMID:9674425)
GO_REF:0000107
GO_REF:0000033		 RGD
Ensembl
GO_Central		 PMID:9674425 PMID:11564863 GO_REF:0000033 GO_REF:0000107 NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769 		JBrowse link
G Trrap transformation/transcription domain-associated protein part_of ISO (PMID:11564863)
(PMID:28893950)		 RGD PMID:11564863 PMID:28893950 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674 		JBrowse link
G Usp22 ubiquitin specific peptidase 22 part_of ISO (PMID:18206972), (PMID:18206973), (PMID:27601583) RGD PMID:18206972 PMID:18206973 PMID:27601583 NCBI chr10:45,828,619...45,855,468
Ensembl chr10:45,828,622...45,855,497 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6599
      catalytic complex 1823
        peptidase complex 136
          SAGA complex 22
Path 2
Term Annotations click to browse term
  cellular_component 20624
    cellular anatomical entity 20384
      organelle 13758
        non-membrane-bounded organelle 5216
          intracellular non-membrane-bounded organelle 5197
            chromosome 1369
              chromatin 811
                histone acetyltransferase complex 93
                  SAGA-type complex 37
                    SAGA complex 22
paths to the root