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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Drug Hypersensitivity Syndrome
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Accession:DOID:9007806 term browser browse the term
Definition:Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s).
Synonyms:exact_synonym: DRESS Syndrome;   DRESS Syndromes;   Drug Hypersensitivity Syndromes;   Drug Reaction with Eosinophilia and Systemic Symptoms;   Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome
 primary_id: MESH:D063926;   RDO:0015829
 xref: EFO:1002004

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Drug Hypersensitivity Syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,007,953...8,010,591
Ensembl chrNW_004936474:8,008,534...8,010,191 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936740:885,855...888,854
Ensembl chrNW_004936740:883,272...890,606 		JBrowse link
G Il1b interleukin 1 beta ISO DNA:SNP:promoter:-511C>T (rs 16944) (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004936783:1,251,678...1,256,807
Ensembl chrNW_004936783:1,252,158...1,257,165 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:SNP:intron:rs2234663 (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004936783:1,447,158...1,466,331
Ensembl chrNW_004936783:1,447,106...1,466,340 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936561:3,017,471...3,035,481
Ensembl chrNW_004936561:3,016,926...3,035,552 		JBrowse link
G LOC101956412 heat shock 70 kDa protein 1-like ISO DNA:polymorphism, haplotype: :p.M493T (human) RGD PMID:15024131 RGD:8662461 NCBI chrNW_004936727:1,735,880...1,745,231
Ensembl chrNW_004936727:1,736,243...1,745,231 		JBrowse link
G LOC101960229 complement C1q subcomponent subunit C ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936474:8,013,395...8,016,937
Ensembl chrNW_004936474:8,013,359...8,016,959 		JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936588:2,638,597...2,640,856
Ensembl chrNW_004936588:2,638,601...2,640,868 		JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004936709:1,578,137...1,741,877
Ensembl chrNW_004936709:1,579,096...1,741,754 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14500
    syndrome 9538
      Drug Hypersensitivity Syndrome 9
Path 2
Term Annotations click to browse term
  disease 14500
    Pathological Conditions, Signs and Symptoms 11297
      Signs and Symptoms 9366
        Neurologic Manifestations 9057
          sensory system disease 6299
            skin disease 3582
              dermatitis 431
                Drug Eruptions 63
                  Drug Hypersensitivity Syndrome 9
paths to the root