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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Drug Hypersensitivity Syndrome
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Accession:DOID:9007806 term browser browse the term
Definition:Severe drug eruption characterized by high fever, erythematous rash and inflammation of internal organ(s).
Synonyms:exact_synonym: DRESS Syndrome;   DRESS Syndromes;   Drug Hypersensitivity Syndromes;   Drug Reaction with Eosinophilia and Systemic Symptoms;   Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome
 primary_id: MESH:D063926;   RDO:0015829
 xref: EFO:1002004

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Drug Hypersensitivity Syndrome term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qa complement C1q A chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624764:7,363,615...7,366,408
Ensembl chrNW_004624764:7,363,567...7,366,617 		JBrowse link
G C1qb complement C1q B chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624764:7,377,013...7,382,953
Ensembl chrNW_004624764:7,376,967...7,383,445 		JBrowse link
G C1qc complement C1q C chain ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624764:7,369,365...7,373,238
Ensembl chrNW_004624764:7,369,338...7,373,436 		JBrowse link
G Crp C-reactive protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624794:1,531,555...1,533,804
Ensembl chrNW_004624794:1,531,571...1,533,804 		JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO DNA:polymorphism, haplotype: :p.M493T (human) RGD PMID:15024131 RGD:8662461 NCBI chrNW_004624754:24,403,438...24,423,477
Ensembl chrNW_004624754:24,416,738...24,424,613 		JBrowse link
G Il1b interleukin 1 beta ISO DNA:SNP:promoter:-511C>T (rs 16944) (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004624749:12,852,128...12,858,478
Ensembl chrNW_004624749:12,852,021...12,858,760 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO DNA:SNP:intron:rs2234663 (human) RGD PMID:23461376 RGD:11051970 NCBI chrNW_004624749:13,210,365...13,224,471
Ensembl chrNW_004624749:13,210,476...13,225,890 		JBrowse link
G Lbp lipopolysaccharide binding protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624842:1,306,299...1,332,269
Ensembl chrNW_004624842:1,301,831...1,332,346 		JBrowse link
G Lrg1 leucine rich alpha-2-glycoprotein 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624828:5,204,031...5,207,097
Ensembl chrNW_004624828:5,203,969...5,207,387 		JBrowse link
G Vwf von Willebrand factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:34142820 NCBI chrNW_004624860:2,843,268...2,973,888
Ensembl chrNW_004624860:2,858,088...2,973,052 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 14090
    syndrome 9294
      Drug Hypersensitivity Syndrome 10
Path 2
Term Annotations click to browse term
  disease 14090
    Pathological Conditions, Signs and Symptoms 10993
      Signs and Symptoms 9105
        Neurologic Manifestations 8809
          sensory system disease 6154
            skin disease 3489
              dermatitis 423
                Drug Eruptions 66
                  Drug Hypersensitivity Syndrome 10
paths to the root