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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Murine Acquired Immunodeficiency Syndrome
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Accession:DOID:9006623 term browser browse the term
Definition:Acquired defect of cellular immunity that occurs in mice infected with mouse leukemia viruses (MuLV). The syndrome shows striking similarities with human AIDS and is characterized by lymphadenopathy, profound immunosuppression, enhanced susceptibility to opportunistic infections, and B-cell lymphomas.
Synonyms:exact_synonym: MAIDS;   Murine AIDS;   Murine Acquired Immune Deficiency Syndrome;   Murine Acquired Immuno Deficiency Syndrome
 primary_id: MESH:D016183


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Murine Acquired Immunodeficiency Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apobec3 apolipoprotein B mRNA editing enzyme catalytic subunit 3 disease_progression ISO associated with Arterivirus Infections RGD PMID:23725696 RGD:40902617 NCBI chr 7:111,433,789...111,453,032
Ensembl chr 7:111,433,764...111,452,922 		JBrowse link
G Cd40 CD40 molecule susceptibility ISO RGD PMID:12438641 RGD:11520795 NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534 		JBrowse link
G Cd40lg CD40 ligand treatment ISO RGD PMID:8642687 RGD:11520796 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Il10 interleukin 10 ISO RGD PMID:23415673 RGD:7364815 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Nfkbia NFKB inhibitor alpha ISO protein:decreased expression:lymph node (mouse) RGD PMID:10429205 RGD:127285021 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Rnasel ribonuclease L ISO associated with Arterivirus Infections RGD PMID:23725696 RGD:40902617 NCBI chr13:65,894,990...65,910,354
Ensembl chr13:65,901,459...65,908,704 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    syndrome 10888
      Murine Acquired Immunodeficiency Syndrome 6
Path 2
Term Annotations click to browse term
  disease 18969
    disease by infectious agent 2215
      viral infectious disease 1677
        RNA Virus Infections 1397
          Retroviridae Infections 218
            Murine Acquired Immunodeficiency Syndrome 6
paths to the root