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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Necrosis
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Accession:DOID:9005749 term browser browse the term
Definition:The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.
Synonyms:exact_synonym: Necroses
 primary_id: MESH:D009336
 alt_id: RDO:0005338
 xref: EFO:0009426


show annotations for term's descendants           Sort by:
Necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO associated with Spinal Cord Injuries RGD PMID:17657312 RGD:2301913 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620 		JBrowse link
G AGT angiotensinogen ISO CTD Direct Evidence: marker/mechanism CTD PMID:1535655 PMID:12606818 NCBI chr14:59,643,030...59,656,835
Ensembl chr14:59,643,292...59,656,833 		JBrowse link
G AHR aryl hydrocarbon receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:25831079 NCBI chr 9:86,511,866...86,555,950
Ensembl chr 9:86,511,369...86,555,943 		JBrowse link
G AIFM1 apoptosis inducing factor mitochondria associated 1 ISO CTD Direct Evidence: therapeutic CTD PMID:16532269 NCBI chr  X:106,676,596...106,708,290
Ensembl chr  X:106,670,520...106,708,317 		JBrowse link
G ANGPT2 angiopoietin 2 ISO mRNA:increased expression:liver, stellate cell, macrophage (rat) RGD PMID:15135347 RGD:2314239 NCBI chr15:37,544,177...37,600,925
Ensembl chr15:37,544,707...37,599,041 		JBrowse link
G APP amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:21839817 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,435,094...189,716,056 		JBrowse link
G ARG2 arginase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23424623 NCBI chr 7:91,343,987...91,385,911
Ensembl chr 7:91,343,988...91,385,909 		JBrowse link
G ATF4 activating transcription factor 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:14604972 NCBI chr 5:8,742,964...8,745,752
Ensembl chr 5:8,742,967...8,745,368 		JBrowse link
G ATG5 autophagy related 5 ISO CTD Direct Evidence: marker/mechanism CTD PMID:20578144 NCBI chr 1:72,343,950...72,520,402
Ensembl chr 1:72,270,799...72,520,396 		JBrowse link
G ATG7 autophagy related 7 ISO CTD Direct Evidence: therapeutic CTD PMID:21081844 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,654 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO CTD Direct Evidence: therapeutic CTD PMID:11781163 PMID:16532269 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G BCR BCR activator of RhoGEF and GTPase ISO CTD Direct Evidence: marker/mechanism CTD PMID:23211037 NCBI chr14:49,208,662...49,322,109
Ensembl chr14:49,208,762...49,322,103 		JBrowse link
G CAST calpastatin ISO CTD Direct Evidence: therapeutic CTD PMID:17323976 NCBI chr 2:103,255,738...103,378,623
Ensembl chr 2:103,255,750...103,378,623 		JBrowse link
G CAT catalase ISO CTD Direct Evidence: therapeutic CTD PMID:9548797 PMID:17309078 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G CCN2 cellular communication network factor 2 ISO mRNA:increased expression:brain (rat) RGD PMID:19395590 RGD:2314511 NCBI chr 1:31,674,398...31,677,697
Ensembl chr 1:31,674,394...31,677,691 		JBrowse link
G CD40LG CD40 ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:22295117 NCBI chr  X:111,778,666...111,788,901
Ensembl chr  X:111,778,493...111,789,709 		JBrowse link
G CDC42 cell division cycle 42 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19430526 NCBI chr 6:80,035,034...80,089,243
Ensembl chr 6:80,035,123...80,089,233 		JBrowse link
G CTF1 cardiotrophin 1 ISO CTD Direct Evidence: therapeutic CTD PMID:23335628 NCBI chr 3:17,539,927...17,545,250
Ensembl chr 3:17,539,941...17,544,396 		JBrowse link
G CTSB cathepsin B ISO CTD Direct Evidence: marker/mechanism CTD PMID:22287159 NCBI chr14:15,014,139...15,035,081
Ensembl chr14:15,011,711...15,033,877 		JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12086689 PMID:12566070 NCBI chr14:141,690,737...141,703,078
Ensembl chr14:141,690,426...141,736,817 		JBrowse link
G DMD dystrophin ISO CTD Direct Evidence: marker/mechanism CTD PMID:22795790 NCBI chr  X:27,028,223...29,650,728
Ensembl chr  X:27,028,231...28,383,840 		JBrowse link
G DPP7 dipeptidyl peptidase 7 ISO CTD Direct Evidence: marker/mechanism CTD PMID:16725115
G EPO erythropoietin treatment ISO associated with Ischemia RGD PMID:22924373 RGD:8655615 NCBI chr 3:8,620,508...8,622,936
Ensembl chr 3:8,620,508...8,622,936 		JBrowse link
G FABP3 fatty acid binding protein 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:18308699 NCBI chr 6:87,943,003...87,950,708
Ensembl chr 6:87,942,790...87,951,610 		JBrowse link
G FAS Fas cell surface death receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:15664267 NCBI chr14:100,927,305...100,954,781
Ensembl chr14:100,927,089...100,956,716 		JBrowse link
G FASLG Fas ligand ISO CTD Direct Evidence: marker/mechanism CTD PMID:15664267 NCBI chr 9:115,068,314...115,075,147
Ensembl chr 9:115,068,090...115,076,464 		JBrowse link
G FGF19 fibroblast growth factor 19 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24699334 NCBI chr 2:3,583,027...3,586,985
Ensembl chr 2:3,582,828...3,587,752 		JBrowse link
G FGF2 fibroblast growth factor 2 treatment ISO associated with Ischemia RGD PMID:22924373 RGD:8655615 NCBI chr 8:101,278,877...101,344,084
Ensembl chr 8:101,278,885...101,343,916 		JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase ISO CTD Direct Evidence: therapeutic CTD PMID:25725130 NCBI chr 5:64,129,678...64,135,194
Ensembl chr 5:64,129,679...64,133,991 		JBrowse link
G GATM glycine amidinotransferase ISO CTD Direct Evidence: marker/mechanism CTD PMID:22061828 NCBI chr 1:126,361,968...126,378,705
Ensembl chr 1:126,361,945...126,380,871 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880025 NCBI chr16:66,162,318...66,208,868 JBrowse link
G HMGB1 high mobility group box 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19783637 PMID:22178603 NCBI chr11:7,195,556...7,321,071 JBrowse link
G IFNG interferon gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:10903806 PMID:10909967 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL17A interleukin 17A ISO CTD Direct Evidence: marker/mechanism CTD PMID:24949944 NCBI chr 7:46,013,584...46,017,161
Ensembl chr 7:46,013,584...46,017,153 		JBrowse link
G IL1RN interleukin 1 receptor antagonist ISO CTD Direct Evidence: therapeutic CTD PMID:1838896 PMID:20644519
G IL6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:7608651 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G KRT18 keratin 18 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19783637 NCBI chr 5:18,217,686...18,221,432
Ensembl chr 5:18,217,691...18,221,429 		JBrowse link
G LGALS3 galectin 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22461450 NCBI chr 1:184,478,639...184,496,155
Ensembl chr 1:184,478,710...184,497,951 		JBrowse link
G LOC100739508 glutathione S-transferase P-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:14710442 NCBI chr 2:5,005,498...5,009,247 JBrowse link
G LOC110258578 interleukin-1 beta-like ISO CTD Direct Evidence: marker/mechanism CTD PMID:10631206 PMID:10903806 PMID:10909967
G LPL lipoprotein lipase ISO CTD Direct Evidence: marker/mechanism CTD PMID:10533957 NCBI chr14:4,104,761...4,134,964
Ensembl chr14:4,104,772...4,135,814 		JBrowse link
G METTL14 methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:34648132 NCBI chr 8:105,019,539...105,053,603
Ensembl chr 8:105,015,420...105,053,563 		JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase ISO CTD Direct Evidence: therapeutic CTD PMID:21619552 NCBI chr14:138,502,005...138,771,543
Ensembl chr14:138,499,309...138,771,540 		JBrowse link
G MIR192 microRNA mir-192 ISO CTD Direct Evidence: marker/mechanism CTD PMID:24880025 NCBI chr 2:7,285,667...7,285,746
Ensembl chr 2:7,285,667...7,285,746 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase ISO CTD Direct Evidence: marker/mechanism CTD PMID:14723717 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:21214410 NCBI chr 3:121,543,201...121,549,678
Ensembl chr 3:121,543,109...121,549,046 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 ISO CTD Direct Evidence: therapeutic CTD PMID:24813929 NCBI chr15:82,967,485...83,146,185
Ensembl chr15:82,973,656...83,146,183 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10620138 PMID:10909967 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 ISO CTD Direct Evidence: therapeutic CTD PMID:30996006 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:7608651 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418 		JBrowse link
G PRNP prion protein ISO CTD Direct Evidence: marker/mechanism CTD PMID:18547651 NCBI chr17:13,694,195...13,705,126
Ensembl chr17:13,694,190...13,705,124 		JBrowse link
G PUF60 poly(U) binding splicing factor 60 ISO CTD Direct Evidence: marker/mechanism CTD PMID:21435101 NCBI chr 4:812,137...824,321
Ensembl chr 4:812,131...824,318 		JBrowse link
G RBP4 retinol binding protein 4 ISO CTD Direct Evidence: marker/mechanism CTD PMID:22061828 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
G RDH13 retinol dehydrogenase 13 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27865848 NCBI chr 6:59,274,383...59,293,139
Ensembl chr 6:59,274,387...59,292,765 		JBrowse link
G SET SET nuclear proto-oncogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:24555657 NCBI chr 1:269,050,447...269,064,462 JBrowse link
G SLC31A1 solute carrier family 31 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19144690 NCBI chr 1:253,868,389...253,893,135
Ensembl chr 1:253,868,332...253,894,449 		JBrowse link
G SOD1 superoxide dismutase 1 ISO CTD Direct Evidence: therapeutic CTD PMID:9548797 NCBI chr13:195,326,573...195,335,273
Ensembl chr13:195,326,649...195,337,729 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:9548797 PMID:19293248 NCBI chr 1:7,679,352...7,689,564
Ensembl chr 1:7,679,352...7,689,560 		JBrowse link
G SOD3 superoxide dismutase 3 ISO CTD Direct Evidence: therapeutic CTD PMID:11529661 NCBI chr 8:18,796,633...18,802,156
Ensembl chr 8:18,796,637...18,802,152 		JBrowse link
G SPARC secreted protein acidic and cysteine rich ISO CTD Direct Evidence: marker/mechanism CTD PMID:23408952 NCBI chr16:71,368,164...71,380,972
Ensembl chr16:71,357,586...71,381,161 		JBrowse link
G TBXA2R thromboxane A2 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:22206755 NCBI chr 2:75,068,413...75,081,305
Ensembl chr 2:75,068,698...75,087,731 		JBrowse link
G TNF tumor necrosis factor ISO CTD Direct Evidence: marker/mechanism CTD PMID:10631206 PMID:10909967 PMID:22345571 PMID:24548419 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G TNNT2 troponin T2, cardiac type ISO CTD Direct Evidence: marker/mechanism CTD PMID:17848144 NCBI chr10:23,749,528...23,759,696
Ensembl chr10:23,749,335...23,763,396 		JBrowse link
ARTHROGRYPOSIS, PERTHES DISEASE, AND UPWARD GAZE PALSY term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NEK9 NIMA related kinase 9 ISO ClinVar Annotator: match by term: Arthrogryposis, Perthes disease, and upward gaze palsy OMIM
ClinVar		 PMID:25741868 PMID:26633546 PMID:28492532 NCBI chr 7:98,275,973...98,322,072
Ensembl chr 7:98,275,979...98,322,055 		JBrowse link
Bisphosphonate-Associated Osteonecrosis of the Jaw term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL1A1 collagen type I alpha 1 chain treatment ISO associated with Multiple Myeloma RGD PMID:21396799 RGD:11041182 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
Femur Head Necrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2M alpha-2-macroglobulin ISO mRNA:increased expression:head of femur RGD PMID:20579363 RGD:10046018 NCBI chr 5:62,406,928...62,483,690
Ensembl chr 5:62,440,810...62,483,678 		JBrowse link
G ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 susceptibility ISO associated with Alcohol-Related Disorders;DNA:SNP:rs13233308 (human) RGD PMID:28422712 RGD:401901196 NCBI chr 9:93,049,955...93,146,469 JBrowse link
G CAT catalase susceptibility ISO DNA:SNPs:multiple: RGD PMID:18353692 RGD:9479160 NCBI chr 2:26,493,664...26,533,881
Ensembl chr 2:26,487,653...26,581,452 		JBrowse link
G COL2A1 collagen type II alpha 1 chain ISO ClinVar Annotator: match by term: Avascular necrosis of femoral head, primary | ClinVar Annotator: match by term: Avascular necrosis of femoral head, primary, 1 OMIM
ClinVar		 PMID:7695699 PMID:7977371 PMID:8218237 PMID:8702139 PMID:8893763 More... NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718 		JBrowse link
G F2 coagulation factor II, thrombin ISO associated with kidney transplantation;20210G>A(human) RGD PMID:16968732 RGD:6902907 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F5 coagulation factor V ISO associated with kidney transplantation;1691G>A(human) RGD PMID:16968732 RGD:6902907 NCBI chr 4:81,403,273...81,484,908
Ensembl chr 4:81,403,274...81,485,066 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:26261616 RGD:11087286 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G IL23R interleukin 23 receptor susceptibility ISO associated with Alcohol-Related Disorders;DNA:SNP:rs6693831 (human) RGD PMID:28422712 RGD:401901196 NCBI chr 6:145,337,765...145,401,909
Ensembl chr 6:145,335,741...145,401,510 		JBrowse link
G LRP5 LDL receptor related protein 5 treatment ISO RGD PMID:24510055 RGD:12793062 NCBI chr 2:4,533,721...4,653,997
Ensembl chr 2:4,533,614...4,653,944 		JBrowse link
G MIA MIA SH3 domain containing ISO mRNA:increased expression:head of femur RGD PMID:20579363 RGD:10046018 NCBI chr 6:48,986,232...49,010,042
Ensembl chr 6:48,986,733...48,988,432 		JBrowse link
G MIR23A microRNA mir-23a ameliorates ISO RGD PMID:29039554 RGD:155882564 NCBI chr 2:65,308,117...65,308,186
Ensembl chr 2:65,308,117...65,308,186 		JBrowse link
G NOS3 nitric oxide synthase 3 susceptibility ISO associated with Alcohol-Related Disorders;DNA:SNPs,haplotype::rs743506,rs3918184 (human) RGD PMID:28422712 RGD:401901196 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
G PLAT plasminogen activator, tissue type ISO DNA:insertion:intron:IVS8 (human) RGD PMID:24025446 RGD:11541046 NCBI chr17:11,195,599...11,223,821
Ensembl chr17:11,195,602...11,224,032 		JBrowse link
G POMC proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:4326745 NCBI chr 3:113,661,712...113,668,558
Ensembl chr 3:113,661,004...113,670,418 		JBrowse link
G TFPI tissue factor pathway inhibitor susceptibility ISO DNA:haplotype: :
protein:increased expression:femur head:		 RGD PMID:18695356 PMID:23063054 RGD:11060260 RGD:11062059 NCBI chr15:92,345,083...92,409,962
Ensembl chr15:92,345,075...92,409,905 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO ClinVar Annotator: match by term: Avascular necrosis of femoral head, primary, 2 OMIM
ClinVar		 PMID:4056805 PMID:8179305 PMID:20037586 PMID:20037587 PMID:20037588 More... NCBI chr14:41,125,819...41,169,582
Ensembl chr14:41,125,869...41,169,578 		JBrowse link
Infarction term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSF3 colony stimulating factor 3 ISO CTD Direct Evidence: therapeutic CTD PMID:15135374 NCBI chr12:22,333,445...22,335,949
Ensembl chr12:22,333,449...22,338,753 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO RGD PMID:12911537 RGD:10395384 NCBI chr 3:94,167,759...94,253,662
Ensembl chr 3:94,165,816...94,254,079 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO RGD PMID:12911537 RGD:10395384 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G POLR2A RNA polymerase II subunit A ISO RGD PMID:22535878 RGD:9681722 NCBI chr12:52,779,833...52,806,210
Ensembl chr12:52,779,828...52,807,598 		JBrowse link
G PRL prolactin ISO CTD Direct Evidence: marker/mechanism CTD PMID:718334 NCBI chr 7:17,451,367...17,463,771
Ensembl chr 7:17,451,367...17,463,710 		JBrowse link
Legg-Calve-Perthes disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G COL2A1 collagen type II alpha 1 chain ISO ClinVar Annotator: match by term: Coxa plana | ClinVar Annotator: match by term: Legg-Calve-Perthes disease | ClinVar Annotator: match by term: Osteochondritis deformans OMIM
ClinVar		 PMID:7695699 PMID:7977371 PMID:8218237 PMID:8702139 PMID:8893763 More... NCBI chr 5:78,350,131...78,380,893
Ensembl chr 5:78,350,137...78,380,718 		JBrowse link
G GNPTAB N-acetylglucosamine-1-phosphate transferase subunits alpha and beta ISO ClinVar Annotator: match by term: Legg-Calve-Perthes disease ClinVar PMID:19617216 PMID:20301728 PMID:23566849 PMID:25505245 PMID:25741868 More... NCBI chr 5:82,264,640...82,460,819
Ensembl chr 5:82,361,872...82,460,814 		JBrowse link
osteonecrosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA2 annexin A2 ISO RGD PMID:15784727 RGD:1578382 NCBI chr 1:111,588,721...111,635,064
Ensembl chr 1:111,588,306...111,635,059 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:19070762 NCBI chr 6:30,059,247...30,087,031
Ensembl chr 6:30,058,595...30,086,982 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase no_association ISO associated with Anemia, Sickle Cell;DNA:SNP: :677C>T (human) RGD PMID:9840906 RGD:10449417 NCBI chr 6:71,863,637...71,882,118
Ensembl chr 6:71,863,637...71,881,820 		JBrowse link
G PLG plasminogen ISO associated with severe acute respiratory syndrome;protein:decreased expression:plasma (human) RGD PMID:16547717 PMID:16677567 RGD:30309948 RGD:30309951 NCBI chr 1:7,062,399...7,109,521
Ensembl chr 1:7,061,192...7,110,555 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa ISO associated with severe acute respiratory syndrome;protein:decreased expression:plasma (human) RGD PMID:16547717 PMID:16677567 RGD:30309948 RGD:30309951 NCBI chr15:25,043,543...25,054,310
Ensembl chr15:25,043,545...25,056,595 		JBrowse link
G SERPINC1 serpin family C member 1 ISO associated with severe acute respiratory syndrome;protein:decreased expression:plasma (human) RGD PMID:16547717 PMID:16677567 RGD:30309948 RGD:30309951 NCBI chr 9:116,181,988...116,193,100
Ensembl chr 9:116,181,670...116,193,201 		JBrowse link
G VWF von Willebrand factor ISO associated with severe acute respiratory syndrome;protein:decreased expression:plasma (human) RGD PMID:16547717 RGD:30309948 NCBI chr 5:64,516,627...64,655,938
Ensembl chr 5:64,519,186...65,002,452 		JBrowse link
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Path 1
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  disease 15274
    Pathological Conditions, Signs and Symptoms 11810
      Pathologic Processes 7355
        Necrosis 90
          DNA Degradation, Necrotic 0
          Fat Necrosis + 0
          Infarction + 5
          dental pulp necrosis 0
          gangrene 0
          osteonecrosis + 26
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