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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:dental caries
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Accession:DOID:216 term browser browse the term
Definition:A teeth hard tissue disease that is characterized by damage to a tooth that can happen when decay-causing bacteria in your mouth make acids that attack the tooth’s surface, or enamel. (DO)
Synonyms:exact_synonym: Carious Dentin;   Dental Decay;   Dental White Spot;   Dental caries extending into pulp;   Dental caries of smooth surface;   Dental caries pit and fissure;   White Spot;   dental white spots;   white spots
 narrow_synonym: smooth surface dental caries
 primary_id: MESH:D003731
 xref: EFO:0003819;   EFO:0006338;   EFO:0006339;   EFO:0600096;   ICD10CM:K02.6;   ICD10CM:K02.9;   ICD9CM:521.0;   ICD9CM:521.07;   NCI:C52593
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
dental caries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcor BCL6 co-repressor susceptibility ISO DNA:SNP: : rs17145638(human) RGD PMID:23470693 RGD:155631274 NCBI chr  X:10,609,756...10,729,613
Ensembl chr  X:10,687,732...10,729,613 		JBrowse link
G Il1b interleukin 1 beta ISO DNA:SNP: :rs1143627C>T (human) RGD PMID:30803280 RGD:14975276 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G RT1-Bb RT1 class II, locus Bb ISO RGD PMID:29594988 RGD:14928324 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597 		JBrowse link
root caries term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin susceptibility ISO RGD PMID:17959907 RGD:11035291 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18976
    Stomatognathic Diseases 1348
      tooth disease 447
        teeth hard tissue disease 119
          dental caries 4
            Curly Hair-Acral Keratoderma-Caries Syndrome 0
            Dental Fissures 0
            Flynn Aird Syndrome 0
            dentin caries 0
            enamel caries 0
            odontoclasia 0
            root caries 1
Path 2
Term Annotations click to browse term
  disease 18976
    Pathological Conditions, Signs and Symptoms 13376
      Signs and Symptoms 10866
        Neurologic Manifestations 10102
          sensory system disease 7022
            mouth disease 1019
              tooth disease 447
                Tooth Demineralization 6
                  dental caries 4
                    Curly Hair-Acral Keratoderma-Caries Syndrome 0
                    Dental Fissures 0
                    Flynn Aird Syndrome 0
                    dentin caries 0
                    enamel caries 0
                    odontoclasia 0
                    root caries 1
paths to the root