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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:thyroid gland anaplastic carcinoma
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Accession:DOID:0080522 term browser browse the term
Definition:A thyroid gland carcinoma that is composed of undifferentiated cells. (DO)
Synonyms:exact_synonym: Thyroid Gland Undifferentiated (Anaplastic) Carcinoma;   anaplastic thyroid cancer;   anaplastic thyroid cancers;   anaplastic thyroid carcinoma;   anaplastic thyroid carcinomas
 primary_id: MESH:D065646
 xref: EFO:1000595;   NCI:C3878


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thyroid gland anaplastic carcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBX7 chromobox 7 IEP
ISO		 mRNA,protein:decreased expression:thyroid gland:
mRNA,protein,DNA:decreased expression, loss of heterozygosity:thyroid gland:
mRNA:decreased expression:thyroid gland:		 RGD PMID:19706751 PMID:18701502 PMID:18701502 RGD:9586729, RGD:9587357, RGD:9587357 NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680 		JBrowse link
G MIR21 microRNA 21 IEP RNA:increased expression:thyroid gland: RGD PMID:20956945 RGD:41404697 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15887859 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G TP53 tumor protein p53 IAGP ClinVar Annotator: match by term: Thyroid gland undifferentiated (anaplastic) carcinoma ClinVar PMID:1565144 PMID:1631137 PMID:2046748 PMID:7732013 PMID:8423216 More... NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 35756
    disease of cellular proliferation 9860
      Neoplasms by Histologic Type 6533
        cell type cancer 4698
          carcinoma 3531
            thyroid gland carcinoma 117
              thyroid gland anaplastic carcinoma 4
Path 2
Term Annotations click to browse term
  disease 35756
    disease of cellular proliferation 9860
      cancer 6816
        organ system cancer 6567
          endocrine gland cancer 2667
            thyroid cancer 129
              thyroid gland carcinoma 117
                thyroid gland anaplastic carcinoma 4
paths to the root