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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:thyroid gland anaplastic carcinoma
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Accession:DOID:0080522 term browser browse the term
Definition:A thyroid gland carcinoma that is composed of undifferentiated cells. (DO)
Synonyms:exact_synonym: Thyroid Gland Undifferentiated (Anaplastic) Carcinoma;   anaplastic thyroid cancer;   anaplastic thyroid cancers;   anaplastic thyroid carcinoma;   anaplastic thyroid carcinomas
 primary_id: MESH:D065646
 xref: EFO:1000595;   NCI:C3878

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thyroid gland anaplastic carcinoma term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CBX7 chromobox 7 ISO mRNA:decreased expression:thyroid gland:
mRNA,protein,DNA:decreased expression, loss of heterozygosity:thyroid gland:
mRNA,protein:decreased expression:thyroid gland:		 RGD PMID:18701502 PMID:19706751 RGD:9586729 RGD:9587357 NCBI chr19:21,776,618...21,798,525
Ensembl chr19:21,775,931...21,798,309 		JBrowse link
G SOD2 superoxide dismutase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:15887859 NCBI chr13:87,284,537...87,297,998
Ensembl chr13:87,280,686...87,297,974 		JBrowse link
G TP53 tumor protein p53 ISO ClinVar Annotator: match by term: Thyroid gland undifferentiated (anaplastic) carcinoma ClinVar PMID:1565144 PMID:1631137 PMID:2046748 PMID:7732013 PMID:8423216 More... NCBI chr16:7,047,686...7,065,567
Ensembl chr16:7,045,146...7,066,223 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 15274
    disease of cellular proliferation 7115
      Neoplasms by Histologic Type 4961
        cell type cancer 3540
          carcinoma 2990
            thyroid gland carcinoma 63
              thyroid gland anaplastic carcinoma 3
Path 2
Term Annotations click to browse term
  disease 15274
    disease of cellular proliferation 7115
      cancer 5154
        organ system cancer 4925
          endocrine gland cancer 2289
            thyroid cancer 74
              thyroid gland carcinoma 63
                thyroid gland anaplastic carcinoma 3
paths to the root