Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:sulfathiazole
go back to main search page
Accession:CHEBI:9337 term browser browse the term
Definition:A 1,3-thiazole compound having a 4-aminobenzenesulfonamido group at the 2-position.
Synonyms:exact_synonym: 4-amino-N-1,3-thiazol-2-ylbenzenesulfonamide
 related_synonym: 2-(Sulfanilylamino)thiazole;   2-(p-Aminobenzenesulfonamido)thiazole;   2-(p-Aminobenzenesulphonamido)thiazole;   2-Sulfanilamidothiazol;   2-Sulfanilamidothiazole;   2-Sulfonamidothiazole;   4-Amino-N-2-thiazolylbenzenesulfonamide;   Formula=C9H9N3O2S2;   InChI=1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12);   InChIKey=JNMRHUJNCSQMMB-UHFFFAOYSA-N;   N(1)-2-Thiazolylsulfanilamide;   SMILES=C=1(C=CC(=CC1)N)S(NC2=NC=CS2)(=O)=O;   Sulfanilamidothiazole;   Sulfatiazol;   Sulphathiazole;   sulfathiazol;   sulfathiazolum;   sulfthiazole
 xref: Beilstein:226178;   CAS:72-14-0;   DrugBank:DB06147;   Drug_Central:2527;   Gmelin:218965;   HMDB:HMDB0015619;   KEGG:C11169;   KEGG:D01047;   LINCS:LSM-5327;   PMID:11431418;   PMID:7486915;   Patent:GB517272;   Patent:US2362087;   Patent:US4665100;   Reaxys:226178;   Wikipedia:Sulfathiazole


show annotations for term's descendants           Sort by:
N-succinylsulfathiazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddit4 DNA-damage-inducible transcript 4 multiple interactions
increases expression		 ISO [Folic Acid deficiency co-treated with succinylsulfathiazole] results in decreased expression of DDIT4 protein
succinylsulfathiazole results in increased expression of DDIT4 protein		 CTD PMID:33957263 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation ISO succinylsulfathiazole results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:33957263 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO succinylsulfathiazole results in decreased phosphorylation of MTOR protein CTD PMID:33957263 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase-1 multiple interactions
decreases expression		 ISO Folic Acid deficiency inhibits the reaction [succinylsulfathiazole results in decreased expression of PDPK1 protein] CTD PMID:33957263 NCBI chr10:13,105,435...13,182,664
Ensembl chr10:13,105,498...13,174,623 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        xenobiotic 18738
          sulfathiazole 4
            N-succinylsulfathiazole 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    main group molecular entity 19786
                      s-block molecular entity 19624
                        hydrogen molecular entity 19611
                          hydrides 19117
                            inorganic hydride 18115
                              pnictogen hydride 18104
                                nitrogen hydride 18011
                                  azane 17821
                                    ammonia 17820
                                      organic amino compound 17820
                                        aromatic amine 15421
                                          anilines 14419
                                            substituted aniline 14061
                                              sulfanilamide 2919
                                                sulfathiazole 4
                                                  N-succinylsulfathiazole 4
paths to the root