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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:glycyrin
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Accession:CHEBI:69086 term browser browse the term
Definition:A member of the class of coumarins that is coumarin substituted by methoxy groups at positions 5 and 7, a prenyl group at position 6 and a 2,4-dihydroxyphenyl group at position 3. Isolated from Glycyrrhiza uralensis, it exhibits antibacterial activity.
Synonyms:exact_synonym: 3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-(3-methylbut-2-en-1-yl)-2H-chromen-2-one
 related_synonym: 3-(2',4'-dihydroxyphenyl)-5,7-dimethoxy-2-isopentenylcoumarin;   3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-(3-methyl-but-2-enyl)-1-benzopyran-2-one;   3-(2,4-dihydroxyphenyl)-5,7-dimethoxy-6-prenylcoumarin;   Formula=C22H22O6;   InChI=1S/C22H22O6/c1-12(2)5-7-15-19(26-3)11-20-17(21(15)27-4)10-16(22(25)28-20)14-8-6-13(23)9-18(14)24/h5-6,8-11,23-24H,7H2,1-4H3;   InChIKey=FWWGXZYUURXJLK-UHFFFAOYSA-N;   SMILES=COc1cc2oc(=O)c(cc2c(OC)c1CC=C(C)C)-c1ccc(O)cc1O
 xref: CAS:66056-18-6;   HMDB:HMDB0033712;   LIPID_MAPS_instance:LMPK12160017
 xref_mesh: MESH:C000602096
 xref: PMID:11575586;   PMID:12127165;   PMID:14608046;   PMID:14643306;   PMID:22074222;   Patent:WO2004064830;   Reaxys:1667250


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glycyrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dyrk1a dual specificity tyrosine phosphorylation regulated kinase 1A decreases activity ISO glycyrin results in decreased activity of DYRK1A protein CTD PMID:31838052 NCBI chr11:33,890,706...34,009,420
Ensembl chr11:33,890,490...34,009,420 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            glycyrin 1
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Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  oxacycle 17889
                                    benzopyran 11958
                                      1-benzopyran 11710
                                        chromenes 4419
                                          chromenone 4372
                                            coumarins 4141
                                              glycyrin 1
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