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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:methomyl
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Accession:CHEBI:6835 term browser browse the term
Definition:A carbamate ester obtained by the formal condensation of methylcarbamic acid with the hydroxy group of 1-(methylsulfanyl)acetaldoxime.
Synonyms:exact_synonym: methyl N-(methylcarbamoyloxy)ethanimidothioate
 related_synonym: 1-(Methylthio)acetaldehyde O-methylcarbamoyloxime;   1-(Methylthio)ethylideneamino methylcarbamate;   Formula=C5H10N2O2S;   InChI=1S/C5H10N2O2S/c1-4(10-3)7-9-5(8)6-2/h1-3H3,(H,6,8);   InChIKey=UHXUZOCRWCRNSJ-UHFFFAOYSA-N;   Lannate;   Methomyl lannate;   N-(((methylamino)carbonyl)oxy)ethanimidothioic acid methyl ester;   S-Methyl N-(methylcarbamoyloxy)thioacetimidate;   SMILES=CNC(=O)ON=C(C)SC
 xref: Beilstein:2042050;   CAS:16752-77-5;   HMDB:HMDB0031804;   KEGG:C11196;   LINCS:LSM-24991
 xref_mesh: MESH:D008724
 xref: PMID:11327381;   PMID:11758270;   PPDB:458;   Pesticides:methomyl;   Reaxys:2042050;   Wikipedia:Methomyl


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methomyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity		 ISO
EXP		 methamidophos promotes the reaction [Methomyl results in decreased activity of ACHE protein]; Methomyl promotes the reaction [methamidophos results in decreased activity of ACHE protein] CTD PMID:8134223 PMID:19371631 PMID:19934164 PMID:21251949 PMID:23962483 More... NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Methomyl results in increased expression of BAX mRNA CTD PMID:34676817 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP [Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein CTD PMID:22649187 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Methomyl results in decreased expression of BCL2 mRNA CTD PMID:34676817 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Casp3 caspase 3 increases expression ISO Methomyl results in increased expression of CASP3 mRNA CTD PMID:34676817 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity ISO Methomyl results in increased activity of CYP19A1 protein CTD PMID:11884232 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Methomyl inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression EXP Methomyl results in increased expression of FSHB protein CTD PMID:11516254 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO Methomyl results in decreased expression of HSP90B1 protein CTD PMID:16271832 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A decreases expression ISO Methomyl results in decreased expression of HSPA1A protein CTD PMID:16271832 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Methomyl results in increased expression of HSPA5 protein CTD PMID:16271832 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 decreases expression ISO Methomyl results in decreased expression of HSPA8 protein CTD PMID:16271832 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Kyat1 kynurenine aminotransferase 1 decreases activity ISO Methomyl results in decreased activity of KYAT1 protein CTD PMID:7175100 NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355 		JBrowse link
G Kynu kynureninase decreases activity ISO Methomyl results in decreased activity of KYNU protein CTD PMID:7175100 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G Lhb luteinizing hormone subunit beta increases expression EXP Methomyl results in increased expression of LHB protein CTD PMID:11516254 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Pgr progesterone receptor multiple interactions ISO Methomyl inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344 		JBrowse link
G Prl prolactin increases expression EXP Methomyl results in increased expression of PRL protein CTD PMID:11516254 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G S100a1 S100 calcium binding protein A1 multiple interactions EXP Methomyl results in increased expression of and affects the localization of S100A1 protein CTD PMID:30472887 NCBI chr 2:175,993,922...175,998,765
Ensembl chr 2:175,993,922...175,999,544 		JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression EXP Methomyl results in increased expression of TPT1 protein CTD PMID:30472887 NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625 		JBrowse link
thiodicarb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO
EXP		 thiodicarb results in decreased activity of ACHE protein CTD PMID:21251949 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      application 19658
        agrochemical 16285
          methomyl 19
            thiodicarb 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            heteroorganic entity 19488
                              organochalcogen compound 19251
                                organosulfur compound 17358
                                  thiocarboxylic acid 19
                                    monothiocarboxylic acid 19
                                      thioacetic acid 19
                                        ethanethioic S-acid 19
                                          S-methyl thioacetate 19
                                            1-(methylsulfanyl)acetaldoxime 19
                                              methomyl 19
                                                thiodicarb 1
paths to the root