Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:benzothiazole
go back to main search page
Accession:CHEBI:45993 term browser browse the term
Definition:An organic heterobicyclic compound that is a fusion product between benzene and thiazole. The parent of the class of benzothiazoles.
Synonyms:exact_synonym: 1,3-benzothiazole
 related_synonym: 1-Thia-3-azaindene;   BT;   Benzosulfonazole;   Benzothiazol;   Formula=C7H5NS;   InChI=1S/C7H5NS/c1-2-4-7-6(3-1)8-5-9-7/h1-5H;   InChIKey=IOJUPLGTWVMSFF-UHFFFAOYSA-N;   SMILES=c1ccc2scnc2c1
 xref: Beilstein:109468;   CAS:95-16-9;   DrugBank:DB08624;   HMDB:HMDB0032930
 xref_mesh: MESH:C005465
 xref: PDBeChem:THZ;   PMID:15750776;   PMID:18568896;   PMID:23500410;   PMID:24248888;   Reaxys:109468;   UM-BBD_compID:c1128;   Wikipedia:Benzothiazole


show annotations for term's descendants           Sort by:
benzothiazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor affects binding ISO benzothiazole binds to AHR protein; benzothiazole metabolite binds to AHR protein CTD PMID:16705413 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ephx1 epoxide hydrolase 1 increases expression EXP benzothiazole results in increased expression of EPHX1 mRNA CTD PMID:8951341 NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235 		JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression EXP benzothiazole results in increased expression of GSTA2 mRNA CTD PMID:8951341 NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP benzothiazole results in increased expression of GSTM1 mRNA CTD PMID:8951341 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression EXP benzothiazole results in increased expression of GSTM2 mRNA CTD PMID:8951341 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        xenobiotic 18738
          benzothiazole 5
            2-hydroxybenzothiazole 0
            2-methylthio-1,3-benzothiazole 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic molecule 19684
                              organic cyclic compound 19496
                                organic heterocyclic compound 18874
                                  organic heteropolycyclic compound 18299
                                    organic heterobicyclic compound 17233
                                      benzothiazoles 151
                                        benzothiazole 5
                                          2-hydroxybenzothiazole 0
                                          2-methylthio-1,3-benzothiazole 0
paths to the root