CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: taurocholate
Accession: CHEBI:36257
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Definition: An organosulfonate oxoanion that is the conjugate base of taurocholic acid.
Synonyms: exact_synonym: 2-[(3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonate
related_synonym: Formula=C26H44NO7S; InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1; InChIKey=WBWWGRHZICKQGZ-HZAMXZRMSA-M; SMILES=[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O
xref: Beilstein:3919947; Reaxys:3919947
cyclic_relationship: is_conjugate_base_of CHEBI:28865
G
Il17a
interleukin 17A
increases expression
EXP
Sodium taurocholate increases expression of Il17a mRNA and protein in the pancreas
RGD
PMID:22990529
RGD:9068935
NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
G
Serpinf1
serpin family F member 1
EXP
taurocholate decreased activity of Serpinf1 protein in plasma
RGD
PMID:10360224
RGD:8661651
NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
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