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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:taurocholate
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Accession:CHEBI:36257 term browser browse the term
Definition:An organosulfonate oxoanion that is the conjugate base of taurocholic acid.
Synonyms:exact_synonym: 2-[(3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholan-24-yl)amino]ethanesulfonate
 related_synonym: Formula=C26H44NO7S;   InChI=1S/C26H45NO7S/c1-15(4-7-23(31)27-10-11-35(32,33)34)18-5-6-19-24-20(14-22(30)26(18,19)3)25(2)9-8-17(28)12-16(25)13-21(24)29/h15-22,24,28-30H,4-14H2,1-3H3,(H,27,31)(H,32,33,34)/p-1/t15-,16+,17-,18-,19+,20+,21-,22+,24+,25+,26-/m1/s1;   InChIKey=WBWWGRHZICKQGZ-HZAMXZRMSA-M;   SMILES=[H][C@@]12C[C@H](O)CC[C@]1(C)[C@@]1([H])C[C@H](O)[C@]3(C)[C@]([H])(CC[C@@]3([H])[C@]1([H])[C@H](O)C2)[C@H](C)CCC(=O)NCCS([O-])(=O)=O
 xref: Beilstein:3919947;   Reaxys:3919947
 cyclic_relationship: is_conjugate_base_of CHEBI:28865



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sodium taurocholate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il17a interleukin 17A increases expression EXP Sodium taurocholate increases expression of Il17a mRNA and protein in the pancreas RGD PMID:22990529 RGD:9068935 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G Serpinf1 serpin family F member 1 EXP taurocholate decreased activity of Serpinf1 protein in plasma RGD PMID:10360224 RGD:8661651 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    chemical entity 19836
      molecular entity 19836
        ion 16705
          anion 16086
            organic anion 3615
              cholanic acid conjugate anion 2
                taurocholate 2
                  sodium taurocholate 2
                  taurocholate 7-sulfate(2-) 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      chalcogen 19543
                        oxygen atom 19518
                          oxygen molecular entity 19518
                            oxide 12757
                              oxoanion 10303
                                chalcogen oxoanion 659
                                  sulfur oxoanion 657
                                    sulfonate 113
                                      organosulfonate oxoanion 113
                                        taurocholate 2
                                          sodium taurocholate 2
                                          taurocholate 7-sulfate(2-) 0
paths to the root