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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:gamma-aminobutyrate
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Accession:CHEBI:30566 term browser browse the term
Definition:An gamma-amino acid anion resulting from the deprotonation of the carboxy group of gamma-aminobutyric acid.
Synonyms:exact_synonym: 4-aminobutanoate
 related_synonym: 4-Amino-butyrat;   4-Aminobutylate;   4-aminobutanoic acid ion (1-);   4-aminobutyrate;   Formula=C4H8NO2;   InChI=1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)/p-1;   InChIKey=BTCSSZJGUNDROE-UHFFFAOYSA-M;   SMILES=NCCCC([O-])=O;   gamma-aminobutanoate;   gamma-aminobutyrate anion
 alt_id: CHEBI:11961;   CHEBI:20317
 xref: Beilstein:3536873;   Gmelin:559138;   KEGG:C00334;   PMID:12509893;   Reaxys:3536873
 cyclic_relationship: is_conjugate_base_of CHEBI:16865


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4-(trimethylammonio)butanoate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bbox1 gamma-butyrobetaine hydroxylase 1 multiple interactions ISO [BBOX1 protein co-treated with Ketoglutaric Acids] results in increased metabolism of gamma-butyrobetaine CTD PMID:21439360 NCBI chr 3:96,822,654...96,871,786
Ensembl chr 3:96,822,655...96,871,458 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions
increases abundance		 ISO Triazines inhibits the reaction [IDH2 protein mutant form results in increased abundance of gamma-butyrobetaine] CTD PMID:27469509 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19838
    role 19814
      biological role 19812
        biochemical role 19522
          metabolite 19509
            butyrate 99
              gamma-aminobutyrate 2
                4-(trimethylammonio)butanoate 2
Path 2
Term Annotations click to browse term
  CHEBI ontology 19838
    subatomic particle 19836
      composite particle 19836
        hadron 19836
          baryon 19836
            nucleon 19836
              atomic nucleus 19836
                atom 19836
                  main group element atom 19786
                    p-block element atom 19786
                      carbon group element atom 19734
                        carbon atom 19731
                          organic molecular entity 19731
                            organic ion 9866
                              organic anion 3615
                                carboxylic acid anion 2480
                                  monocarboxylic acid anion 1591
                                    fatty acid anion 130
                                      short-chain fatty acid anion 123
                                        fatty acid anion 4:0 99
                                          butyrate 99
                                            gamma-aminobutyrate 2
                                              4-(trimethylammonio)butanoate 2
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